Optical coherence tomography angiography features in patients with idiopathic full-thickness macular hole, before and after surgical treatment

Figures & data

Figure 1 Pre- and postoperative FAZ measurement using a nonflow software in an 82-year-old male patient.

Note: FAZ decreased from 0.405 mm² preoperatively to 0.152 mm² postoperatively.
Abbreviation: FAZ, foveal avascular zone.

Figure 2 The fovea vessel density (FVDS) measured in superficial capillary plexus (SCP) using a density function on the imaging software.

Notes: In vascular density color perfusion maps, bright red represents a density of greater than 50% perfused vessels, dark blue represents no perfused vessels, and intermediate perfusion densities are color coded accordingly. In presented case example of 82-year-old male patient, the increase of FVDS from 29.83% to 38.73% after surgery is to observe. The ischemic areas decreased significantly. We observe a reduction of central retinal thickness from 531 to 253 µm postoperatively.

Figure 3 Pre- and postoperative choriocapillary flow area measurement using a flow tool of imaging software.

Note: This example shows a case of 82-year-old male patient with an increase in choriocapillary flow area from 0.768 mm² preoperatively to 1.914 mm² postoperatively.

Figure 4 Pre- and post- operative OCTA of 82-year-old patient’s left eye.

Notes: (A) Preoperative OCTA report of 82-year-old male patient’s left eye showing numerous cystic changes in middle retina in en face scans. Macular basal hole size is 2,146 µm, minimum hole diameter is 427 µm. BCVA preoperatively was 0.08. (B) Postoperative OCTA scans of the same case as presented above. We observe in OCTA and en face scans the resolution of macular hole and adjacent cystic areas with normalization of foveal morphology and reduction of central retinal thickness. BCVA improved to 0.3 after surgery.

Abbreviations: BCVA, best-corrected visual acuity; OCT, optical coherence tomography; OCTA, optical coherence tomography angiography.

Figure 5 Pre- and post- operative OCTA of 75-year-old patient’s right eye.

Notes: (A) Preoperative OCTA report of 75-year-old female patient’s right eye showing numerous cysts in middle retina in en face scans. Macular basal hole size is 1,565 µm, minimum hole diameter is 699 µm. BCVA preoperatively was 0.08. (B) Postoperative OCTA scans of the same patient as presented above. We observe in OCTA and en face scans the resolution of macular hole and adjacent cystic areas with reduction of central retinal thickness. BCVA improved to 0.4 after surgery.
Abbreviations: BCVA, best-corrected visual acuity; OCT, optical coherence tomography; OCTA, optical coherence tomography angiography.

Figure 6 The r-Pearson correlation coefficient between the initial MHS and the BCVA.

Notes: (A) Relationship between preoperative macular hole size (MHS) and best-corrected visual acuity (BCVA). (B) Relationship between preoperative MHS and macular parafoveal choriocapillary flow. (C) Relationship between preoperative FAZ and postoperative BCVA. (D) Relationship between postoperative BCVA and postoperative CRT.
Abbreviations: CRT, central retinal thickness; FAZ, foveal avascular zone.