Identification of potentially inappropriate medications with risk of major adverse cardiac and cerebrovascular events among elderly patients in ambulatory setting and long-term care facilities

João Pedro Aguiar1 Research Institute for Medicines (iMED.ULisboa), Faculdade de Farmácia, Universidade de Lisboa, Lisboa, Portugal, [email protected]Correspondence[email protected]

Luís Heitor Costa2 Serviço de Medicina Interna, Centro Hospitalar Psiquiátrico de Lisboa (CHPL), Lisboa, Portugal

Filipa Alves da Costa3 Centro de Investigação Interdisciplinar Egas Moniz (CiiEM), Instituto Universitário Egas Moniz (IUEM), Caparica, Portugal;4 Faculdade de Farmácia, Universidade de Lisboa, Lisboa, Portugal

Hubert GM Leufkens5 Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, the Netherlands

Ana Paula Martins1 Research Institute for Medicines (iMED.ULisboa), Faculdade de Farmácia, Universidade de Lisboa, Lisboa, Portugal, [email protected]

Identification of potentially inappropriate medications with risk of major adverse cardiac and cerebrovascular events among elderly patients in ambulatory setting and long-term care facilities

Table 1 Sociodemographic and clinical features of the Portuguese elderly sample

Table 2 Number of patients using PIMs associated with risk of CCVAE or MACCE

Table 3 Most commonly prescribed pharmacotherapeutic groups associated with risk of CCVAEs in both settings

Table 4 Most commonly prescribed PIMs associated with risk of MACCE in both settings

Table S1 Potentially inappropriate medications with risk of cardiovascular adverse events in the elderly

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Identification of potentially inappropriate medications with risk of major adverse cardiac and cerebrovascular events among elderly patients in ambulatory setting and long-term care facilities

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Table 1 Sociodemographic and clinical features of the Portuguese elderly sample

Table 2 Number of patients using PIMs associated with risk of CCVAE or MACCE

Table 3 Most commonly prescribed pharmacotherapeutic groups associated with risk of CCVAEs in both settings

Table 4 Most commonly prescribed PIMs associated with risk of MACCE in both settings

Table S1 Potentially inappropriate medications with risk of cardiovascular adverse events in the elderly

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