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Clinical Interventions in Aging Volume 7, 2012 - Issue
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Review

Effectiveness of influenza vaccine in aging and older adults: comprehensive analysis of the evidence

Pierre-Olivier Lang1 Department of Internal Medicine, Rehabilitation and Geriatrics, University Hospitals and Medical School of Geneva, Geneva, Switzerland;2 Translational Medicine Research Group, Cranfield Health, Cranfield University, Cranfield, EnglandCorrespondence[email protected]
,
Aline Mendes1 Department of Internal Medicine, Rehabilitation and Geriatrics, University Hospitals and Medical School of Geneva, Geneva, Switzerland
,
Jennifer Socquet1 Department of Internal Medicine, Rehabilitation and Geriatrics, University Hospitals and Medical School of Geneva, Geneva, Switzerland
,
Noémie Assir1 Department of Internal Medicine, Rehabilitation and Geriatrics, University Hospitals and Medical School of Geneva, Geneva, Switzerland
,
Sheila Govind2 Translational Medicine Research Group, Cranfield Health, Cranfield University, Cranfield, England
&
Richard Aspinall2 Translational Medicine Research Group, Cranfield Health, Cranfield University, Cranfield, England
Pages 55-64 | Published online: 24 Feb 2012

Figures & data

Figure 1 Development of immunosenescence with advancing age and its impact on the ability of the immune system to respond to influenza virus antigen. Potential impacts of immunotherapy of immunosenescence are also presented.

Abbreviations: CMV, cytomegalovirus; IL, interleukin; TIV, trivalent inactivated influenza vaccine; TNF-α, tumor necrosis factor-alpha.
Figure 1 Development of immunosenescence with advancing age and its impact on the ability of the immune system to respond to influenza virus antigen. Potential impacts of immunotherapy of immunosenescence are also presented.

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