Orthostatic Hypotension in Elderly Patients with Essential Tremor

Figures & data

Table 1 Demographic and Clinical Characteristics of the Participants in the Study

	ET n=44	Healthy Controls n=118	p
Age (y)	72.8±6.1	72.7±6.7	0.971
Gender female n (%)	30 (68.2)	94 (79.7)	0.125
Hypertension (%)	72.7	61.9	0.135
Diabetes mellitus (%)	22.7	31.4	0.282
Coronary artery disease (%)	34.1	11	0.001
Charlson Comorbidity Index	0.95±0.83	0.85±1.01	0.239
Drugs (n)	5.2±2.8	5.0±3.4	0.465
OH 1st n, (%)	14 (31.8)	21 (17.8)	0.046
OH 3rd n, (%)	12 (27.3)	26 (22)	0.484
OH 5th n, (%)	10 (22.7)	25 (21.2)	0.918
HBA1C (%)	6.8±1.1	7.3±1.8	0.684
TSH (mIU/L)	1.8±1.1	1.7±1.5	0.473
Beta blockers (%)	59.1	30.5	0.001
Antihypertensive drugs* (%)	68.3	58.1	0.251
SSRI (%)	45.5	28.8	0.046

Notes: *Includes calcium channel blockers, diüretic, ACE inhibitors, ARB inhibitors. Statistically significant differences are shown bold and the significance level is 0.05.

Abbreviations: ET, essential tremor; n, number; OH, orthostatic hypotension; %, percent; SSRI, selective serotonin reuptake inhibitors; TSH, thyroid-stimulating hormone; y, years.

Table 2 The Demographic and Clinical Features of Patients with Essential Tremor

	OH (+) n=14	OH (−) n=30	P
Age (y), mean± SD	74.5±5.2	72±6.5	0.300
Gender M n, (%)	6 (42.9)	8 (26.7)	0.232
Disease duration (y), mean± SD	14.1±8.7	19.7±13.7	0.343
FTMTR scale*	38 (6–60)	30 (4–63)	0.314
Family history of ET (%)	13 (92.9)	23 (76.7)	0.194**
Voice tremor (%)	3 (21.4)	13 (43.3)	0.159
Head tremor (%)	3 (21.4)	6 (20)	0.603*
Jaw tremor (%)	5 (35.7)	2 (6.7)	0.025**
MMSE*	28 (25–30)	28 (22–30)	0.802
Geriatric Depression Scale*	2 (0–12)	2 (0–12)	0.724
Basic ADL score*	95 (80–100)	95 (75–100)	0.927
Instrumental ADL score*	22 (11–23)	22 (13–13)	0.557
4-meter-walking speed m/sec*	1 (0.8–1.33)	0.96 (0.38–1.73)	0.973
TUG test, seconds*	11.89 (7–22)	11 (6–24)	0.485
POMA-total score*	27 (19–28)	28 (14–28)	0.333
Beta-blockers n (%)	9 (64.3)	17 (56.7)	0.632

Notes: Statistically significant differences are shown bold and the significance level is 0.05. *Median (minimum-maximum); **Fisher’s exact test.

Abbreviations: ADL, activities of daily living; FTMTR Fahn-Tolosa-Marin Tremor Rating Scale; M, male; MMSE, mini-mental state examination test; POMA, Tinetti Performance-Oriented Mobility Assessment; SD, standard deviation; TUG, timed up and go test; y, years.