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Original Research

Plasma Amyloid-β Oligomerization Tendency Predicts Amyloid PET Positivity

, , , , ORCID Icon, , , , , ORCID Icon & ORCID Icon show all
Pages 749-755 | Published online: 30 Apr 2021

Figures & data

Figure 1 Concentration of plasma MDS-OAβ according to groups.

Abbreviations: AD, Alzheimer’s disease; MCI, mild cognitive impairment; MDS-OAβ, Multimer Detection System-Oligomeric Amyloid-β; OND, other neurodegenerative disease; SCD, subjective cognitive decline.
Figure 1 Concentration of plasma MDS-OAβ according to groups.

Table 1 Demographics and Clinical Characteristics of Subjects

Table 2 Performance of Predictors for Amyloid PET Positivity with and without MDS-OAβ Positivity

Figure 2 Receiver operating characteristic analysis of MDS-OAβ positivity with other predictors on amyloid PET positivity. (A) Added MDS-OAβ positivity to clinical information such as age, MMSE score, and APOE ε4 status, predictability for amyloid PET positivity improves. (B) Considered only objective factors such as age and APOE ε4 status, combining with MDS-OAβ positivity strengthened the predictability on amyloid PET positivity.

Abbreviations: MDS-OAβ, Multimer Detection System-Oligomeric Amyloid-β; MMSE, Mini-Mental-State-Examination.
Figure 2 Receiver operating characteristic analysis of MDS-OAβ positivity with other predictors on amyloid PET positivity. (A) Added MDS-OAβ positivity to clinical information such as age, MMSE score, and APOE ε4 status, predictability for amyloid PET positivity improves. (B) Considered only objective factors such as age and APOE ε4 status, combining with MDS-OAβ positivity strengthened the predictability on amyloid PET positivity.