Risk Factors for New Vertebral Fracture After Percutaneous Vertebroplasty for Osteoporotic Vertebral Compression Fractures

Figures & data

Table 1 Univariate Analysis of New Vertebral Fracture After Vertebroplasty

	Fracture Group (n=362) (%)	Non-Fracture Group (1840) (%)	t/x^2 value	P value
Age (yrs)	69.32±4.426	65.80±4.045	−14.020	0.000
Sex (%)			18.268	0.000
Male	61 (16.9)	508 (27.6)
Female	301 (83.1)	1332 (72.4)
Height(cm)	159.75±8.386	158.94±8.737	−1.635	0.102
Body weight (kg)	59.74±8.623	59.32±6.710	−0.879	0.380
Preoperative bone mineral density (kg/cm3)	3.259±0.4094	3.220±0.4169	−1.619	0.106
Number of fractured vertebrae	1.31±0.605	1.33±0.635	0.488	0.626
Injection volume of bone cement in a single vertebrae (mL)	4.645±1.1732	4.581±0.6974	−1.000	0.318
Leakage rate of bone cement (%)			1.699	0.192
Yes	115 (31.8)	522 (28.4)
No	247 (68.2)	1318 (71.6)
Smoking (%)			7.825	0.005
Yes	55 (15.2)	187 (10.2)
No	307 (84.8)	1653 (89.8)
Alcohol consumption (%)			7.098	0.008
Yes	46 (12.7)	153 (8.3)
No	316 (87.3)	1687 (91.7)
Diabetes (%)			8.511	0.004
Yes	109 (30.1)	422 (22.9)
No	253 (69.9)	1418 (77.1)
Hypertension (%)			1.526	0.217
Yes	106 (29.3)	481 (26.1)
No	256 (70.7)	1359 (73.9)
Coronary heart disease (%)			0.207	0.649
Yes	77 (21.3)	372 (20.2)
No	285 (78.7)	1468 (79.8)
Chronic obstructive pulmonary disease (%)			0.995	0.319
Yes	49 (13.5)	287 (15.6)
No	313 (86.5)	1553 (84.4)
Postoperative exercise (%)			200.444	0.000
Yes	171 (47.2)	1507 (81.9)
No	191 (52.8)	333 (18.1)
Postoperative osteoporosis treatment (%)			44.125	0.000
Yes	77 (21.3)	730 (39.7)
No	285 (78.7)	1110 (60.3)

Table 2 Multivariate Logistic Regression Analysis of New Vertebral Fracture After Vertebroplasty

Variable	Partial Regression Coefficient	Standard Error	Wald value	P value	Odds Ratio	Odds Ratio 95% CI
						Lower	Upper
Age (yr)	0.193	0.016	141.264	0.000	1.212	1.174	1.252
Sex	0.651	0.168	15.008	0.000	1.917	1.379	2.665
Smoking	0.431	0.193	4.989	0.026	1.538	1.054	2.245
Alcohol consumption	0.075	0.208	0.126	0.719	1.078	0.717	1.620
Diabetes	0.650	0.146	19.751	0.000	1.915	1.438	2.551
Postoperative exercise	−1.516	0.134	127.709	0.000	0.220	0.169	0.286
Postoperative osteoporosis treatment	−0.884	0.155	32.340	0.000	0.413	0.305	0.560

Abbreviation: CI, confidence interval.

Figure 1 Risk factores of new vertebral fracture after vertebroplasty.