Treatment of postherpetic neuralgia: focus on pregabalin

Figures & data

Table 1 Dosage adjustment of pregabalin based on renal clearance²⁰

Creatinine clearance (ml/min)	Total daily dose of pregabalin (mg/day)				Total daily dose to be divided
≥60	150	300	450	600	2–3 times daily
30–59	75	150	225	300	2–3 times daily
15–29	25–50	75	100–150	150	Once or twice daily
<15	25	25–50	50–75	75	Once daily
Supplemental dose after HDa	25–50	50–75	75–100	100–150

^aSupplemental dose after hemodialysis is a single dose to be administered after each 4-hour hemodialysis session.

Abbreviation: HD, hemodialysis.

Lyrica® [package insert]New York: Pfizer Inc; 62007

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