Age-Related Changes in Trabecular Bone Score and Bone Mineral Density in Chinese Men: A Cross-Sectional and Longitudinal Study

Figures & data

Table 1 Baseline Characteristics of the Study Population

Subgroup (Age in Years)	Age (Year)	n	Follow-Up Interval (Year)	BMI (kg/m^2)
36–45	42.1±2.8	30	3.2(0.9–7.6)	26.4±3.3
46–55	50.7±2.7	97	3.0(0.9–7.2)	25.7±2.6
56–65	60.0±2.6	87	3.0(0.9–7.8)	25.3±2.6
66–75	70.3±2.9	39	2.7(0.9–6.8)	24.7±2.8
76–85	80.6±2.8	37	4.0(1.0–7.4)	24.5±3.3
Total	59.0±11.7	290	3.0(0.9–7.8)	24.3±2.0

Notes: Data were presented as median (min-maximum) and mean ± SD.

Abbreviation: BMI, body mass index.

Figure 1 Average bone mineral density (BMD) at the total hip (TH), femoral neck (FN), and lumbar spine (LS) in 10-year age subgroups. P for trend according to the 10-year age subgroups using linear trend test.

Figure 2 Average bone mineral density (BMD) from L1 to L4 separately in 10-year age subgroups. P for trend according to the 10-year age subgroups using linear trend test.

Figure 3 Average trabecular bone score (TBS) at the lumbar spine (LS) in 10-year age subgroups. P for trend according to the 10-year age subgroups using quadratic term trend test.

Table 2 Average Annual Change Rate (%/Year) of BMD at Each Site and LS TBS in 10-Year Age Subgroups

Subgroup (Age in Years)	LS BMD (%/Year)^a*	FN BMD (%/Year)	TH BMD (%/Year)	LS TBS (%/Year)
36–45	−0.21±2.44	0.02±2.44	0.48±1.95	−0.17±2.55
46–55	0.68±1.61	−0.01±2.61	−0.03±2.00	−0.21±2.52
56–65	0.78±1.67	−0.31±1.62	0.17±2.08	0.13±2.18
66–75	1.05±2.01	0.12±2.18	0.23±1.91	−1.08±2.7^b**
76–85	1.26±1.88	0.04±2.01	0.27±1.52	−0.18±1.62
Total	0.77±1.83	−0.09±2.15	0.16±1.95	−0.17±2.36

Notes: Data are shown as mean ± SD. ^aEach age subgroup was tested for trend using trend ANOVA. *P for trend <0.01. ^bUsed the LSD test with ANOVA, comparing the age subgroup of 66–75 years to the remaining subgroup, **P<0.05.

Abbreviations: LS BMD, lumbar spine bone mineral density; FN BMD, femoral neck bone mineral density; TH BMD, total hip bone mineral density; LS TBS, lumbar spine trabecular bone score.