A model for estimating body shape biological age based on clinical parameters associated with body composition

Figures & data

Table 1 Clinical characteristics of study subjects by gender

Parameters	Males (n = 132,336)		Females (n = 110,042)
	Mean ± SD	Range	Mean ± SD	Range
Age (years)	47.17 ± 10.98	20.00~90.00	46.94 ± 11.95	20.00~90.00
Ht (cm)	170.57 ± 5.96	141.00~190.00	157.91 ± 5.63	140.00~189.00
Wt (kg)	71.16 ± 9.23	37.50~100.00	56.92 ± 7.64	31.00~99.80
BMI (kg/m^2)	24.25 ± 2.45	15.01~30.01	22.65 ± 2.72	15.01~30.01
LBM%	72.26 ± 4.11	52.39~85.00	65.51 ± 4.64	52.01~85.00
BFM%	23.30 ± 4.58	10.00~42.98	29.85 ± 4.82	10.00~43.00
WC (cm)	84.83 ± 4.78	60.00~105.00	77.07 ± 6.08	60.00~105.00
HC (cm)	95.51 ± 1.79	76.50~110.00	92.74 ± 1.96	75.00~110.00
WHR	0.90 ± 0.03	0.67~1.19	0.83 ± 0.04	0.66~1.18

Abbreviations: SD, standard deviation; Ht, height; Wt, weight; BMI, body mass index; LBM%, lean body mass percentage; BFM%, body fat mass percentage; WC, waist circumference; HC, hip circumference; WHR, waist-to-hip ratio.

Table 2 Correlation coefficients between age and clinical parameters in males

Parameters	Males (n = 132,336)	P-value
Ht	−0.38	<0.001
Wt	−0.21	<0.001
BMI	0.01	0.191
LBM%	−0.14	<0.001
BFM%	0.15	<0.001
WC	0.16	<0.001
HC	−0.45	<0.001
WHR	0.79	<0.001

Abbreviations: Ht, height; Wt, weight; BMI, body mass index; LBM%, lean body mass percentage; BFM%, body fat mass percentage; WC, waist circumference; HC, hip circumference; WHR, waist-to-hip ratio.

Table 3 Correlation coefficients between age and clinical parameters in females

Parameters	Females (n = 110,042)	P-value
Ht	−0.46	<0.001
Wt	0.14	<0.001
BMI	0.41	<0.001
LBM%	−0.43	<0.001
BFM%	0.41	<0.001
WC	0.58	<0.001
HC	0.52	<0.001
WHR	0.86	<0.001

Abbreviations: Ht, height; Wt, weight; BMI, body mass index; LBM%, lean body mass percentage; BFM%, body fat mass percentage; WC, waist circumference; HC, hip circumference; WHR, hip-to-waist ratio.

Table 4 Body shape biological age prediction model in males (R² = 0.705)

Parameters	PRC ± SEM	Standard PRC	t	P-value
WHR	281.419 ± 0.922	0.692	305.362	0.000
HC	−1.595 ± 0.014	−0.260	−114.282	0.000
Ht	−0.149 ± 0.005	−0.081	−27.987	0.000
LBM%	−0.112 ± 0.007	−0.042	−15.500	0.000
Wt	−0.052 ± 0.004	−0.043	−13.681	0.000

Abbreviations: PRC, partial regression coefficients; SEM, standard error of the mean; WHR, waist-to-hip ratio; HC, hip circumference; Ht, height; LBM%, lean body mass percentage; Wt, weight.

Table 5 Body shape biological age prediction model in females (R² = 0.763)

Parameters	PRC ± SEM	Standard PRC	t	P-value
WHR	224.964 ± 0.922	0.768	244.049	0.000
Ht	−0.245 ± 0.005	−0.115	−49.171	0.000
HC	−0.631 ± 0.016	0.103	40.325	0.000
LBM%	−0.200 ± 0.006	−0.077	−32.074	0.000
WC	−0.123 ± 0.006	−0.063	−20.244	0.000

Abbreviations: PRC, partial regression coefficients; SEM, standard error of the mean; WHR, waist-to-hip ratio; Ht, height; HC, hip circumference; LBM%, lean body mass percentage; WC, waist circumference.

Figure 1 The body shape BA prediction model in males.

Notes: The 45° line represents the theoretical normal aging line in males. The experimental line is the predicted regression line on body shape BA, and both dotted lines mean the range of ± 1 standard deviation (67%). The equation: body shape BA: −16.958 + 281.419 (WHR) − 1.595 (HC) − 0.149 (Ht) − 0.112 (LBM%) − 0.052 (Wt).

Abbreviations: BA, biological age; WHR, waist-to-hip ratio; HC, hip circumference; Ht, height; LBM%, lean body mass percentage; Wt, weight.

Figure 2 The body shape and BA prediction model in females.

Notes: The 45° line represents the theoretical normal aging line in females. The experimental line is the predicted regression line on body shape BA and both dotted lines mean the range of 67%. The equation: body shape BA: −137.388 + 224.964 (WHR) − 0.245 (Ht) + 0.631 (HC) − 0.2 (LBM%) − 0.123 (WC).
Abbreviations: BA, biological age; WHR, waist-to-hip ratio; Ht, height; HC, hip circumference; LBM%, lean body mass percentage; WC, waist circumference.