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Clinical Interventions in Aging Volume 8, 2013 - Issue
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Short Report

Rifampicin-resistant Mycobacterium leprae in an elderly leprosy patient in the people’s Republic of China

Meiwen Yu1 Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, National Center for STD and Leprosy Control, China CDC, Nanjing, People’s Republic of China
,
Kan Wu1 Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, National Center for STD and Leprosy Control, China CDC, Nanjing, People’s Republic of China
,
Bing Pei2 Department of Infectious Diseases, Shanghai Skin Disease Hospital, Shanghai, People’s Republic of China
,
Degang Yang2 Department of Infectious Diseases, Shanghai Skin Disease Hospital, Shanghai, People’s Republic of China
,
Qiulin Wang1 Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, National Center for STD and Leprosy Control, China CDC, Nanjing, People’s Republic of China
,
Hongsheng Wang1 Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, National Center for STD and Leprosy Control, China CDC, Nanjing, People’s Republic of ChinaCorrespondence[email protected]
,
Jianping Shen1 Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, National Center for STD and Leprosy Control, China CDC, Nanjing, People’s Republic of China
,
Liangbing Yan1 Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, National Center for STD and Leprosy Control, China CDC, Nanjing, People’s Republic of China
&
Guochen Zhang1 Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, National Center for STD and Leprosy Control, China CDC, Nanjing, People’s Republic of China
 show all
Pages 1097-1099 | Published online: 21 Aug 2013

Figures & data

Figure 1 (A) Microscopic observation of numerous acid fast bacilli (red rods) in the slit skin smear fluid from a solitary lesion in the face at the initial presentation of the patient. Original magnification: ×1,000. (B) primers used in this study. The letters F and R refer to forward and reverse primer, respectively. (C) Amplification products of folP, gyrA, and rpoB genes (lanes 1–3, respectively). (D) A mutation of codon 441 of the rpoB gene was found (GAt→AAC) (indicated in red).

Figure 1 (A) Microscopic observation of numerous acid fast bacilli (red rods) in the slit skin smear fluid from a solitary lesion in the face at the initial presentation of the patient. Original magnification: ×1,000. (B) primers used in this study. The letters F and R refer to forward and reverse primer, respectively. (C) Amplification products of folP, gyrA, and rpoB genes (lanes 1–3, respectively). (D) A mutation of codon 441 of the rpoB gene was found (GAt→AAC) (indicated in red).

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