Relation between the ankle-brachial index and the complexity of coronary artery disease in older patients

Figures & data

Table 1 Clinical characteristics of the patients in each group

Variables	Total sample: 204 (100%)		P-value
	Group 1 ABI ≤0.9 (N=93)	Group 2 ABI >0.9 (N=111)
ABIa	0.73 (0.57–0.81)	1.03 (0.98–1.10)	NA
Agea (years)	74 (69–78)	71 (67–76)	0.057
Female sex	53 (56.9%)	46 (41.4%)	0.027
Systemic hypertension	86 (92.4%)	98 (88.2%)	0.317
Diabetes mellitus	36 (38.7%)	36 (32.4%)	0.35
Dyslipidemia	50 (53.7%)	59 (53.1%)	0.931
Smoking	33 (35.4%)	26 (23.4%)	0.058
Acute coronary syndrome	64 (68.8%)	36 (32.4%)	0.0001

Note:

a Values expressed as median and interquartile range.

Abbreviations: ABI, ankle-brachial index; NA, not applicable.

Table 2 Angiographic characteristics of patients in each group

Variables	Total sample: 204 (100%)		P-value
	Group 1 ABI ≤0.9 (N=93)	Group 2 ABI >0.9 (N=111)
Without CAD	14 (15%)	46 (41.4%)	<0.0001
Median number of lesions per patient	2 (1–3)	1 (0–2)	<0.0001
Multivessel	50 (53.7%)	34 (30.6%)	0.001
Patients with B2- or C-type lesions	56 (60.2%)	35 (31.5%)	<0.0001
SYNTAX score	12 (5–17.5)	3 (0–12)	<0.0001

Note: The figures for Median number of lesions per patient and SYNTAX score are expressed as median and interquartile range.

Abbreviations: CAD, coronary artery disease; ABI, ankle-brachial index.

Table 3 Angiographic characteristics of patients with coronary artery disease

Variables	Population with CAD: 144 (70.6%)		P-value
	Group 1 ABI ≤0.9 (N=79)	Group 2 ABI >0.9 (N=65)
Median number of lesions per patient	2 (1–3)	3 (1–3)	0.061
Left main involvement	5 (6.3%)	3 (4.6%)	0.65
Multivessel	50 (63.2%)	34 (52.3%)	0.23
Patients with B2- or C-type lesions	56 (70.8%)	35 (53.8%)	0.039
SYNTAX scorea	13 (7–18)	9 (5–19.5)	0.148
SYNTAX score ≥13b	47 (59.4%)	28 (43%)	0.04
SYNTAX score >16c	27 (34.1%)	18 (27.6%)	0.471
SYNTAX score >17d	23 (29.1%)	18 (27.6%)	0.851
SYNTAX score ≥33e	4 (8%)	0 (0%)	0.143

Notes:

a Median SYNTAX score in the population with CAD =12 (range: 5.25–18.75)

b highest tertile of SYNTAX score in Acute Catheterization and Urgent Intervention Triage Strategy (ACUITY) trial

c highest tertile of SYNTAX score in Limus Eluted from A Durable versus ERodable Stent coating (LEADERS) trial

d highest tertile of SYNTAX score in RESOLUTE trial

e highest tertile of SYNTAX score in Syntax Trial, including only patients with multivessel disease. The figures for Median number of lesions per patient and SYNTAX score are expressed as median and interquartile range.

Abbreviations: CAD, coronary artery disease; ABI, ankle-brachial index.