Figures & data
Figure 1 Percentage of patients receiving treatment as a function of average cumulative volume of injected product per treatment period and corresponding average level of improvement from baseline, as measured by the Wrinkle Severity Rating Scale (WSRS).
Table 1 Responders according to the Wrinkle Severity Rating Scale (WSRS) and Global Aesthetic Improvement Scale (GAIS) based on the assessment of medical researchers: percentage of subjects maintaining a clinically significant correction of the nasolabial folds during the study phase
Figure 2 Degree of satisfaction of treatment effects according to study subjects’ self-assessment (%).
Table 2 Average number of applications per year and average amount of injected product
Table 3 Number and distribution of adverse effects in those who suffered from them during the study’s 36-month period
Table 4 Intensity and duration of adverse events in those who suffered from them
Figure 3 A 48-year-old female (Wrinkle Severity Rating Scale grade 3) before and after application of 0.6 mL/side of cross-linked carboxymethyl cellulose and reapplication of 0.5 mL/side at Month 9.
Notes: (A) Before treatment; (B) Month 3; (C) Month 6; (D) Month 9 before reapplication; (E) Month 9 after reapplication; (F) Month 12; (G) Month 18.
Figure 4 A 38-year-old female (Wrinkle Severity Rating Scale grade 4) before and after application of 0.8 mL/side of cross-linked carboxymethyl cellulose and reapplication of 0.6 mL/side at Month 9.
