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Clinical Interventions in Aging Volume 10, 2015 - Issue
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Short Report

The therapeutic effects of bone marrow mesenchymal stem cells after optic nerve damage in the adult rat

HaiBo Tan1 Department of Ophthalmology, RenJi Hospital, The School of Medicine, Shanghai JiaoTong University, Shanghai, People’s Republic of China
,
Xin Kang2 Department of Clinical Pharmacology, Changhai Hospital Affiliated Second Military Medical University, Shanghai, People’s Republic of China
,
ShiHeng Lu1 Department of Ophthalmology, RenJi Hospital, The School of Medicine, Shanghai JiaoTong University, Shanghai, People’s Republic of China
&
Lin Liu1 Department of Ophthalmology, RenJi Hospital, The School of Medicine, Shanghai JiaoTong University, Shanghai, People’s Republic of ChinaCorrespondence[email protected]
Pages 487-490 | Published online: 16 Feb 2015

Figures & data

Figure 1 Representative photomicrographs of regenerating axons in all groups after ONC.

Notes: The numbers of axons/section are presented as the mean ± SD (n=10). (A) asterisk, the crush site; arrow heads, GAP-43 immunofluorescence; scale bar, 50 μm. (B) **P<0.001 compared with the PBS group; #P<0.05 compared with the low BMSC group.
Abbreviations: ONC, optic nerve crush; SD, standard deviation; BMSC, bone marrow mesenchymal stem cell; PBS, phosphate buffered saline.
Figure 1 Representative photomicrographs of regenerating axons in all groups after ONC.

Figure 2 Western blot analysis of GAP-43 expression.

Notes: *P<0.001, compared with the PBS group; #P<0.05, compared with the low BMSC group.
Abbreviations: BMSC, bone marrow mesenchymal stem cell; IB, immunoblotting; PBS, phosphate buffered saline.
Figure 2 Western blot analysis of GAP-43 expression.

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