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Original Research

Cognitive fluctuations in connection to dysgraphia: a comparison of Alzheimer’s disease with dementia Lewy bodies

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Pages 625-633 | Published online: 26 Mar 2015

Figures & data

Table 1 Example scoring list of 14 questions presented to a hypothetical AD patient in PQ1 phase and PQ2 phase. These are routine questions which a doctor can ask to the patient

Figure 1 The performance of AD patient X and DLB patient X during PQ1, followed by the letter-writing test, followed by PQ2.

Note: The quality of handwriting, coherence, and comprehension is taken into account before deciding to terminate the writing session.
Abbreviations: AD, Alzheimer’s disease; DLB, dementia Lewy bodies; PQ1, initial cognition test; PQ2, repeated cognition test.
Figure 1 The performance of AD patient X and DLB patient X during PQ1, followed by the letter-writing test, followed by PQ2.

Table 2 Clinical, demographic, and neuropsychological data of the study groups

Table 3 The Student’s t-test values between PQ1 and PQ2 scores (means ± SD) and Pearson product moment correlational analyses between 1) PQ1 and XF, 2) XF and D∆ over 10 days of testing (days 1, 3, 5, 7, 9, 11, 13, 15, 17, and 19)

Table 4 Younger, less impaired AD patient Student’s t-test values between PQ1 and PQ2 scores (means ± SD) and Pearson product moment correlational analyses between 1) PQ1 and XF, 2) XF and DΔ over 10 days of testing (days 1, 3, 5, 7, 9, 11, 13, 15, 17, and 19)

Table 5 Pearson product moment correlations analyses between MMSE, debut (years), PQ1, XF, PQ2, and DΔ in the 30 AD patients and 26 DLB patients

Figure 2 Examples of cognitive impairment: AD patient scores for ♦PQ1 (before writing) and ■PQ2 (after writing).

Abbreviations: AD, Alzheimer’s disease; PQ1, initial cognition test; PQ2, repeated cognition test.

Figure 2 Examples of cognitive impairment: AD patient scores for ♦PQ1 (before writing) and ■PQ2 (after writing).Abbreviations: AD, Alzheimer’s disease; PQ1, initial cognition test; PQ2, repeated cognition test.

Figure 3 Examples of cognitive impairment: DLB patient scores for ♦PQ1 (before writing) and ■PQ2 (after writing).

Abbreviations: DLB, dementia Lewy bodies; PQ1, initial cognition test; PQ2, repeated cognition test.
Figure 3 Examples of cognitive impairment: DLB patient scores for ♦PQ1 (before writing) and ■PQ2 (after writing).

Figure 4 The difference (DΔ) between cognitive performance in PQ1 and PQ2 by AD patients and DLB patients expressed as DΔ means summated over all 10 days of testing.

Note: Values expressed as mean AD > DLB.
Abbreviations: AD, Alzheimer’s disease; DLB, dementia Lewy bodies; PQ1, initial cognition test; PQ2, repeated cognition test.
Figure 4 The difference (DΔ) between cognitive performance in PQ1 and PQ2 by AD patients and DLB patients expressed as DΔ means summated over all 10 days of testing.

Figure 5 The amount of time spent writing clearly by AD patients and DLB patients expressed as means in the graphia test summated over all 12 days of testing.

Note: Values expressed as mean DLB < AD.
Abbreviations: AD, Alzheimer’s disease; DLB, dementia Lewy bodies.
Figure 5 The amount of time spent writing clearly by AD patients and DLB patients expressed as means in the graphia test summated over all 12 days of testing.