The chance of a live birth after assisted reproduction in women with thyroid disorders

Line Riis Jølving1 Center for Clinical Epidemiology, Odense University Hospital, Odense, Denmark;2 Research Unit of Clinical Epidemiology, Department of Clinical Research, University of Southern Denmark, Odense, DenmarkCorrespondence[email protected]

Michael Due Larsen1 Center for Clinical Epidemiology, Odense University Hospital, Odense, Denmark;2 Research Unit of Clinical Epidemiology, Department of Clinical Research, University of Southern Denmark, Odense, Denmark

Jens Fedder3 Centre of Andrology and Fertility Clinic, Department D, Odense University Hospital, Odense, Denmark;4 Research Unit of Human Reproduction, Department of Clinical Research, University of Southern Denmark, Odense, Denmark

https://orcid.org/0000-0001-5383-5501

Sonia Friedman1 Center for Clinical Epidemiology, Odense University Hospital, Odense, Denmark;2 Research Unit of Clinical Epidemiology, Department of Clinical Research, University of Southern Denmark, Odense, Denmark;5 Crohn’s and Colitis Center, Brigham and Women’s Hospital, Boston, MA, USA;6 Division of Gastroenterology, Hepatology and Endoscopy Research, Harvard Medical School, Boston, MA, USA

Bente Mertz Nørgård1 Center for Clinical Epidemiology, Odense University Hospital, Odense, Denmark;2 Research Unit of Clinical Epidemiology, Department of Clinical Research, University of Southern Denmark, Odense, Denmark;5 Crohn’s and Colitis Center, Brigham and Women’s Hospital, Boston, MA, USA;6 Division of Gastroenterology, Hepatology and Endoscopy Research, Harvard Medical School, Boston, MA, USA

Figures & data

Table 1 Descriptive characteristics of study cohorts of assisted reproductive technology (ART) treatments (embryo transfers) in women with hyperthyroidism, hypothyroidism, and without thyroid disorders, during the study period of 1 January 1994 to 30 June 2017

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Table 2 The chance of a biochemical pregnancy and a clinical pregnancy in women with hyperthyroidism and hypothyroidism after assisted reproductive technology (ART) treatments (embryo transfers), during the study period of 1 January 1994 to 30 June 2017

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Table 3 The chance of live birth in women with hyperthyroidism and hypothyroidism after assisted reproductive technology (ART) treatments (embryo transfers), during the study period of 1 January 1994–30 June 2017

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Table 4 Crude and adjusted ORs, with 95% CI, for congenital malformations (CMs) in live born children, conceived with assisted reproductive technology (ART) treatments of women with hyperthyroidism and hypothyroidism, compared with children born to women without thyroid disease. Study period from 1 January 2006 to 30 June 2016, and followed until 30 June 2017

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Table S1 Types of congenital malformations (CMs) in the children born by women with hypothyroidism from 1 January 2006 to June 2016, and followed until 30 June 2017

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Table S2 Types of congenital malformations (CMs) in the children born by women with hyperthyroidism from 1 January 2006 to June 2016, and followed until 30 June 2017

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The chance of a live birth after assisted reproduction in women with thyroid disorders

Table 1 Descriptive characteristics of study cohorts of assisted reproductive technology (ART) treatments (embryo transfers) in women with hyperthyroidism, hypothyroidism, and without thyroid disorders, during the study period of 1 January 1994 to 30 June 2017

Table 2 The chance of a biochemical pregnancy and a clinical pregnancy in women with hyperthyroidism and hypothyroidism after assisted reproductive technology (ART) treatments (embryo transfers), during the study period of 1 January 1994 to 30 June 2017

Table 3 The chance of live birth in women with hyperthyroidism and hypothyroidism after assisted reproductive technology (ART) treatments (embryo transfers), during the study period of 1 January 1994–30 June 2017

Table S1 Types of congenital malformations (CMs) in the children born by women with hypothyroidism from 1 January 2006 to June 2016, and followed until 30 June 2017

Table S2 Types of congenital malformations (CMs) in the children born by women with hyperthyroidism from 1 January 2006 to June 2016, and followed until 30 June 2017

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The chance of a live birth after assisted reproduction in women with thyroid disorders

Figures & data

Table 1 Descriptive characteristics of study cohorts of assisted reproductive technology (ART) treatments (embryo transfers) in women with hyperthyroidism, hypothyroidism, and without thyroid disorders, during the study period of 1 January 1994 to 30 June 2017

Table 2 The chance of a biochemical pregnancy and a clinical pregnancy in women with hyperthyroidism and hypothyroidism after assisted reproductive technology (ART) treatments (embryo transfers), during the study period of 1 January 1994 to 30 June 2017

Table 3 The chance of live birth in women with hyperthyroidism and hypothyroidism after assisted reproductive technology (ART) treatments (embryo transfers), during the study period of 1 January 1994–30 June 2017

Table S1 Types of congenital malformations (CMs) in the children born by women with hypothyroidism from 1 January 2006 to June 2016, and followed until 30 June 2017

Table S2 Types of congenital malformations (CMs) in the children born by women with hyperthyroidism from 1 January 2006 to June 2016, and followed until 30 June 2017

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