Figures & data
Figure 1 Mendelian randomization association of genetically predicted smoking with overall, ER-positive, and ER-negative breast cancer. Smoking initiation was defined ever being a regular smoker in the life (current or former). Lifetime smoking index is a continuous measure constructed with smoking status (current, former, never), age at smoking initiation and cessation, cigarettes smoked per day, and smoking duration and time since cessation, which is significantly associated with lung cancer risk. Odds ratios are scaled to per 2.72-fold (1-unit log-odds) increase in genetically predicted smoking initiation, and per one standard deviation (corresponds to an individual smoking 20 cigarettes a day for 15 years and stopping 17 years ago, or smoking 60 cigarettes a day for 13 years and stopping 22 years ago) increase in the genetically predicted lifetime smoking index.
