Completeness of TNM cancer staging for melanoma in the Danish Cancer Registry, 2004–2009

Figures & data

Table 1 Completeness of TNM staging among melanoma patients in the Danish Cancer Registry

	Total number of patients	TNM completeness		T completeness		N completeness		M completeness
		n	% (95% CI)	n	% (95% CI)	n	% (95% CI)	n	% (95% CI)
Total	8762	6869	78.4 (77.5–79.3)	7754	88.5 (87.8–89.2)	7424	84.7 (84.0–85.5)	7770	88.7 (88.0–89.3)
Gender
Female	4844	3880	80.1 (79.0–81.2)	4345	89.7 (88.8–90.5)	4153	85.7 (84.7–86.7)	4326	89.3 (88.4–90.2)
Male	3918	2989	76.3 (74.9–77.6)	3409	87.0 (85.9–88.0)	3271	83.5 (82.3–84.6)	3444	87.9 (86.9–88.9)
Age group (years)
0–39	1615	1349	83.5 (81.7–85.3)	1497	92.7 (91.4–93.9)	1417	87.7 (86.1–89.3)	1474	91.3 (89.8–92.6)
40–59	2845	2299	80.8 (79.3–82.2)	2546	89.5 (88.3–90.6)	2459	86.4 (85.1–87.7)	2569	90.3 (89.2–91.4)
60–79	3334	2556	76.7 (75.2–78.1)	2899	87.0 (85.8–88.1)	2805	84.1 (82.9–85.3)	2935	88.0 (86.9–89.1)
≥80	968	665	68.7 (65.7–71.6)	812	83.9 (81.5–86.1)	743	76.8 (74.0–79.3)	792	81.8 (79.3–84.2)
Year of diagnosis
2004	1152	867	75.3 (72.7–77.7)	958	83.2 (80.9–85.2)	978	84.9 (82.7–86.9)	1005	87.2 (85.2–89.1)
2005	1400	1115	79.6 (77.5–81.7)	1228	87.7 (85.9–89.4)	1221	87.2 (85.4–88.9)	1265	90.4 (88.7–91.8)
2006	1430	1152	80.6 (78.5–82.6)	1311	91.7 (90.2–93.0)	1244	87.0 (85.2–88.7)	1301	91.0 (89.4–92.4)
2007	1481	1156	78.1 (75.9–80.1)	1314	88.7 (87.0–90.3)	1220	82.4 (80.4–84.3)	1302	87.9 (86.2–89.5)
2008	1478	1125	76.1 (73.9–78.2)	1315	89.0 (87.3–90.5)	1227	83.0 (81.0–84.9)	1273	86.1 (84.3–87.8)
2009	1821	1454	79.8 (78.0–81.6)	1628	89.4 (87.9–90.8)	1534	84.2 (82.5–85.9)	1624	89.2 (87.7–90.6)
CCI score
Low (0)	6722	5401	80.3 (79.4–81.3)	6031	89.7 (89.0–90.4)	5801	86.3 (85.5–87.1)	6029	89.7 (89.0–90.4)
Medium (1–2)	1559	1144	73.4 (71.1–75.5)	1328	85.2 (83.4–86.9)	1260	80.8 (78.8–82.7)	1334	85.6 (83.8–87.3)
High (3+)	481	324	67.4 (63.1–71.4)	395	82.1 (78.5–85.4)	363	75.5 (71.5–79.2)	407	84.6 (81.2–87.6)
Subanalysis	8762	7011	80.0 (79.2–80.8)

Abbreviations: CI, confidence interval; CCI, Charlson Comorbidity Index (excluding melanoma); TNM, tumor, node, metastasis.

Table 2 Staging of melanoma patients in the Danish Cancer Registry by year of diagnosis, gender, age group, and CCI score

	Cancer stage
	Localized		Regional		Distant		Unknown stage		Known stage
	n	%	n	%	n	%	n	%	n	%
Total	6621	75.6	660	7.5	367	4.2	1114	12.7	7648	87.3
Gender
Female	3825	79.0	305	6.3	155	3.2	559	11.5	4285	88.5
Male	2796	71.4	355	9.1	212	5.4	555	14.2	3363	85.8
Age group (years)
0–39	1327	82.2	102	6.3	33	2.0	153	9.5	1462	90.5
40–59	2179	76.6	240	8.4	121	4.3	305	10.7	2540	89.3
60–79	2434	73.0	278	8.3	169	5.1	453	13.6	2881	86.4
≥80	681	70.4	40	4.1	44	4.5	203	21.0	765	79.0
Year of diagnosis
2004	808	70.1	108	9.4	53	4.6	183	15.9	969	84.1
2005	1066	76.1	112	8.0	63	4.5	159	11.4	1241	88.6
2006	1126	78.7	106	7.4	58	4.1	140	9.8	1290	90.2
2007	1106	74.7	111	7.5	58	3.9	206	13.9	1275	86.1
2008	1118	75.6	107	7.2	66	4.5	187	12.7	1291	87.3
2009	1397	76.7	116	6.4	69	3.8	239	13.1	1582	86.9
CCI score
Low (0)	5204	77.4	522	7.8	216	3.2	780	11.6	5942	88.4
Medium (1–2)	1114	71.5	111	7.1	86	5.5	248	15.9	1311	84.1
High (3+)	303	63.0	27	5.6	65	13.5	86	17.9	395	82.1

Abbreviation: CCI, Charlson Comorbidity Index (excluding melanoma).

Appendix 1 Algorithm for staging of melanoma according to the TNM classification

Stage	TNM classification
Localized	T1 Nx M0, x
	T1–2 N0 Mx
	T1–4, x N0 M0
Regional	T1–4, x N1–3 M0
Distant	T1–4, x N0–3, x M1
Unknown	T1–4, x N1–3 Mx
	T2–4, x Nx M0, x
	T3–4, x N0 Mx

Note: 24 patients (0.3%) coded with T0, Ta, or Tis were added to the unknown stage category, since these codes are not clinically meaningful for melanoma.

Abbreviation: TNM, tumor, node, metastasis.