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Clinical Epidemiology Volume 14, 2022 - Issue
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ORIGINAL RESEARCH

Epidemiology of Disorders Associated with Short Stature in Childhood: A 20-Year Birth Cohort Study in Finland

Samuli Harju1 Institute of Clinical Medicine, School of Medicine, University of Eastern Finland, Kuopio, Finland;2 Department of Paediatrics, Kuopio University Hospital, Kuopio, FinlandCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-5798-2303View further author information
ORCID Icon,
Antti Saari1 Institute of Clinical Medicine, School of Medicine, University of Eastern Finland, Kuopio, Finland;2 Department of Paediatrics, Kuopio University Hospital, Kuopio, FinlandView further author information
,
Reijo Sund1 Institute of Clinical Medicine, School of Medicine, University of Eastern Finland, Kuopio, FinlandORCID Iconhttps://orcid.org/0000-0002-6268-8117View further author information
ORCID Icon &
Ulla Sankilampi1 Institute of Clinical Medicine, School of Medicine, University of Eastern Finland, Kuopio, Finland;2 Department of Paediatrics, Kuopio University Hospital, Kuopio, FinlandView further author information
Pages 1205-1214 | Received 29 Apr 2022, Accepted 23 Sep 2022, Published online: 26 Oct 2022

Figures & data

Figure 1 Flowchart of the study population and register data.

Abbreviation: CRCH, Care Register of Health Care.
Figure 1 Flowchart of the study population and register data.

Table 1 Cumulative Incidences and Median Ages at Diagnosis of Disorders Associated with Short Stature

Figure 2 Cumulative incidence of Turner syndrome (TS), other short-stature syndromes (SSS), and growth hormone deficiency (GHD) from birth to 16 years of age. Cumulative incidence of GHD increases steeply from 4 years onwards both in boys and girls, whereas before 4 years of age, the primary growth disorders are more common.

Figure 2 Cumulative incidence of Turner syndrome (TS), other short-stature syndromes (SSS), and growth hormone deficiency (GHD) from birth to 16 years of age. Cumulative incidence of GHD increases steeply from 4 years onwards both in boys and girls, whereas before 4 years of age, the primary growth disorders are more common.

Figure 3 Cumulative incidence of celiac disease (CD), hypothyroidism (HT), and Crohn’s disease (CrD) from birth to 16 years of age.

Figure 3 Cumulative incidence of celiac disease (CD), hypothyroidism (HT), and Crohn’s disease (CrD) from birth to 16 years of age.

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