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Clinical Epidemiology Volume 15, 2023 - Issue
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ORIGINAL RESEARCH

Disease Burden of Total and Early-Onset Colorectal Cancer in China from 1990 to 2019 and Predictions of Cancer Incidence and Mortality

Bule Shao1 Department of Gastroenterology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, People’s Republic of China;2 Institute of Gastroenterology, Zhejiang University, Hangzhou, People’s Republic of ChinaORCID Iconhttps://orcid.org/0000-0002-8328-9393View further author information
ORCID Icon,
Mengjia Zhu1 Department of Gastroenterology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, People’s Republic of ChinaView further author information
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Kai Shen1 Department of Gastroenterology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, People’s Republic of China;2 Institute of Gastroenterology, Zhejiang University, Hangzhou, People’s Republic of ChinaView further author information
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Liang Luo1 Department of Gastroenterology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, People’s Republic of China;2 Institute of Gastroenterology, Zhejiang University, Hangzhou, People’s Republic of ChinaORCID Iconhttps://orcid.org/0000-0002-2630-5828View further author information
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Ping Du1 Department of Gastroenterology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, People’s Republic of China;2 Institute of Gastroenterology, Zhejiang University, Hangzhou, People’s Republic of ChinaView further author information
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Jun Li1 Department of Gastroenterology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, People’s Republic of China;2 Institute of Gastroenterology, Zhejiang University, Hangzhou, People’s Republic of ChinaView further author information
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Jing Xu3 Department of Pathology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, People’s Republic of ChinaView further author information
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Yanyong Deng1 Department of Gastroenterology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, People’s Republic of China;2 Institute of Gastroenterology, Zhejiang University, Hangzhou, People’s Republic of ChinaView further author information
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Ne Lin1 Department of Gastroenterology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, People’s Republic of China;2 Institute of Gastroenterology, Zhejiang University, Hangzhou, People’s Republic of ChinaView further author information
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Jiaguo Wu1 Department of Gastroenterology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, People’s Republic of China;2 Institute of Gastroenterology, Zhejiang University, Hangzhou, People’s Republic of ChinaCorrespondence[email protected] [email protected]
View further author information
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Weiling Hu1 Department of Gastroenterology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, People’s Republic of China;2 Institute of Gastroenterology, Zhejiang University, Hangzhou, People’s Republic of China;4 Cancer Center, Zhejiang University, Hangzhou, People’s Republic of ChinaView further author information
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Pages 151-163 | Received 29 Sep 2022, Accepted 23 Jan 2023, Published online: 01 Feb 2023

Figures & data

Table 1 Average Annual Percent Change of Epidemiological Metrics of Total CRC and EOCRC in China from 1990 to 2019

Figure 1 Prevalence and age-standardized prevalence rate (A and B), incidence and age-standardized incidence rate (C and D) of total CRC and EOCRC by sex from 1990 to 2019 in China.

Abbreviations: CRC, colorectal cancer; EOCRC, early-onset colorectal cancer.
Figure 1 Prevalence and age-standardized prevalence rate (A and B), incidence and age-standardized incidence rate (C and D) of total CRC and EOCRC by sex from 1990 to 2019 in China.

Figure 2 Number of deaths and age-standardized mortality rate (A and B), total DALYs and age-standardized DALYs rate (C and D) of total CRC and EOCRC by sex from 1990 to 2019 in China.

Abbreviations: CRC, colorectal cancer; EOCRC, early-onset colorectal cancer; DALYs, disability-adjusted life years.
Figure 2 Number of deaths and age-standardized mortality rate (A and B), total DALYs and age-standardized DALYs rate (C and D) of total CRC and EOCRC by sex from 1990 to 2019 in China.

Figure 3 Observed and forecasted temporal trends of age-standardized rates of incidence and death (A and B), incident cases (C and D), and deaths (E and F) of total CRC and EOCRC by sex from 1990 to 2044 in China.

Abbreviations: CRC, colorectal cancer; EOCRC, early-onset colorectal cancer.
Figure 3 Observed and forecasted temporal trends of age-standardized rates of incidence and death (A and B), incident cases (C and D), and deaths (E and F) of total CRC and EOCRC by sex from 1990 to 2044 in China.

Table 2 Observed Number of Incident Cases and Deaths of Total CRC and EOCRC for Both Sex from 1990 to 2019 and Its Prediction from 2020 to 2044

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