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Review

Role of intestinal flora in colorectal cancer from the metabolite perspective: a systematic review

, , , , &
Pages 199-206 | Published online: 31 Jan 2018

Figures & data

Figure 1 Literature search strategy.

Notes: The databases “PubMed”, “Embase”, and “Cochrane” were searched for literature published up to August 11, 2017. Forty-two articles were assessed for eligibility after identification and screening. To present a more comprehensive role of flora in colorectal cancer, the flora appearing in the 42 articles were used as the medical subject headings (MeSH) and the pertinent literature was retrieved. A further 15 articles were added after identification and screening.

Figure 1 Literature search strategy.Notes: The databases “PubMed”, “Embase”, and “Cochrane” were searched for literature published up to August 11, 2017. Forty-two articles were assessed for eligibility after identification and screening. To present a more comprehensive role of flora in colorectal cancer, the flora appearing in the 42 articles were used as the medical subject headings (MeSH) and the pertinent literature was retrieved. A further 15 articles were added after identification and screening.

Figure 2 Network for the intestinal flora and microbial metabolites in colorectal cancer.

Notes: An association network of the intestinal flora and microbial metabolites in colorectal cancer from a metabolic perspective was constructed by analyzing the previous literature. The black and blue arrows represent pathogenic bacteria as well as probiotics, respectively. References are located within the square parentheses.

Figure 2 Network for the intestinal flora and microbial metabolites in colorectal cancer.Notes: An association network of the intestinal flora and microbial metabolites in colorectal cancer from a metabolic perspective was constructed by analyzing the previous literature. The black and blue arrows represent pathogenic bacteria as well as probiotics, respectively. References are located within the square parentheses.