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Cancer Management and Research Volume 10, 2018 - Issue
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Original Research

Recurrence risk after preoperative biopsy in patients with resected early-stage non-small-cell lung cancer: a retrospective study

Chengping Hu1 Department of Respiratory and Critical Care Medicine, National Key Clinical Specialty, Xiangya Hospital, Central South University, Changsha, China, [email protected]
,
Juan Jiang1 Department of Respiratory and Critical Care Medicine, National Key Clinical Specialty, Xiangya Hospital, Central South University, Changsha, China, [email protected]
,
Yuanyuan Li1 Department of Respiratory and Critical Care Medicine, National Key Clinical Specialty, Xiangya Hospital, Central South University, Changsha, China, [email protected]Correspondence[email protected]
,
Chunfang Zhang2 Department of Thoracic Surgery, Xiangya Hospital, Central South University, Changsha, China
,
Weixing Zhang2 Department of Thoracic Surgery, Xiangya Hospital, Central South University, Changsha, China
,
Haihe Jiang2 Department of Thoracic Surgery, Xiangya Hospital, Central South University, Changsha, China
,
Yang Gao2 Department of Thoracic Surgery, Xiangya Hospital, Central South University, Changsha, China
,
Wei Zhuang2 Department of Thoracic Surgery, Xiangya Hospital, Central South University, Changsha, China
,
Kaibo Lei2 Department of Thoracic Surgery, Xiangya Hospital, Central South University, Changsha, China
,
Yong Tang2 Department of Thoracic Surgery, Xiangya Hospital, Central South University, Changsha, China
&
Rongjun Wan1 Department of Respiratory and Critical Care Medicine, National Key Clinical Specialty, Xiangya Hospital, Central South University, Changsha, China, [email protected]
 show all
Pages 1927-1934 | Published online: 06 Jul 2018

Figures & data

Table 1 Baseline characteristics of patients with resected early-stage NSCLC

Table 2 Recurrence patterns of patients with resected early-stage NSCLC

Figure 1 Preoperative percutaneous needle biopsy and bronchoscopic biopsy did not increase recurrence incidence in NSCLC patients.

Notes: (A) DFS curves for patients who had percutaneous needle biopsy or intraoperative biopsy. (B) DFS curves for patients who had bronchoscopic biopsy or intraoperative biopsy.

Abbreviations: DFS, disease-free survival; IOB, intraoperative biopsy; NSCLC, non-small-cell lung cancer; PNB, percutaneous needle biopsy.

Figure 1 Preoperative percutaneous needle biopsy and bronchoscopic biopsy did not increase recurrence incidence in NSCLC patients.Notes: (A) DFS curves for patients who had percutaneous needle biopsy or intraoperative biopsy. (B) DFS curves for patients who had bronchoscopic biopsy or intraoperative biopsy.Abbreviations: DFS, disease-free survival; IOB, intraoperative biopsy; NSCLC, non-small-cell lung cancer; PNB, percutaneous needle biopsy.

Table 3 Subgroup analysis of recurrence risk in NSCLC patients who underwent percutaneous needle biopsy

Table 4 Subgroup analysis of recurrence risk in NSCLC patients who underwent bronchoscopic biopsy

Table 5 Univariate analysis of prognostic factors for DFS in NSCLC patients after radical resection

Table 6 Multivariate analysis of prognostic factors for DFS in NSCLC patients after radical resection

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