Prognostic value of tumor burden in nasopharyngeal carcinoma

Figures & data

Table 1 Patients’ characteristics

Characteristics		No. of patients (%)
Age (years)	Median	45
	Range	10–86
	≥50	356 (35.9%)
	<50	639 (64.4%)
Gender	Male	770 (77.6%)
	Female	222 (22.4%)
TNM stage	T1/T2/T3/T4	125/230/428/209 (12.6%/23.2%/43.1%/21.1%)
	N0/N1/N2/N3	324/440/150/78 (32.7%/44.3%/15.1%/7.9%)
	I/II/III/IV	52/228/443/269 (5.2%/23.0%/44.7%/27.1%)

Figure 1 Cumulative survival curves according to primary tumor volume (TV).

Figure 2 Cumulative survival curves according to nodal volume (NV).

Figure 3 The 5-year overall survival curves for the 16 subgroups and the corresponding establishment of groups, G1–G4.

Table 2 Treatment outcomes of the different tumor burden

Prognostic factors	Five-year LRRF	Five-year DFFR	Five-year DFS	Five-year OS
G1	96.9%	94.8%	91.7%	95.8%
G2	91.9%	91.1%	81.7%	88.9%
G3	88.1%	76.1%	65.4%	79.2%
G4	87.6%	77.2%	60.6%	68.9%
P	0.012	<0.001	<0.001	<0.001

Abbreviations: DFFR, distant failure-free rate; DFS, disease-free survival; LRRF, local regional relapse free; OS, overall survival.

Figure 4 Cumulative survival curves according to tumor burden.

Figure 5 Cumulative survival curves according to AJCC TNM-staging (seventh edition, 2010).²³

Abbreviation: AJCC, American Joint Committee on Cancer.

EdgeSByrdDRComptonCCAJCC cancer staging handbook from the AJCC cancer staging manual7th edNew York20106379

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