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Original Research

Comparison and validation of the value of preoperative inflammation marker-based prognostic scores in resectable pancreatic ductal adenocarcinoma

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Pages 3405-3417 | Published online: 11 Sep 2018

Figures & data

Table 1 Baseline characteristics of patients

Table 2 ROC curve analyses of the NLR, PLR, LMR, and PNI for 1-year DFS

Figure 1 ROC curves of NLR, PLR, LMR, and PNI for 1-year DFS.

Note: (A) NLR, (B) PLR, (C) LMR, and (D) PNI.

Abbreviations: AUC, area under the curve; DFS, disease-free survival; LMR, lymphocyte-monocyte ratio; NLR, neutrophil-lymphocyte ratio; PLR, platelet-lymphocyte ratio; PNI, prognostic nutritional index; ROC, receiver operating characteristic.

Figure 1 ROC curves of NLR, PLR, LMR, and PNI for 1-year DFS.Note: (A) NLR, (B) PLR, (C) LMR, and (D) PNI.Abbreviations: AUC, area under the curve; DFS, disease-free survival; LMR, lymphocyte-monocyte ratio; NLR, neutrophil-lymphocyte ratio; PLR, platelet-lymphocyte ratio; PNI, prognostic nutritional index; ROC, receiver operating characteristic.

Table 3 Baseline characteristics stratified by NLR and PLR

Figure 2 Kaplan–Meier curves of NLR and PLR for DFS and OS.

Notes: (A) NLR for DFS, (B) PLR for DFS, (C) NLR for OS, (D) PLR for OS.

Abbreviations: DFS, disease-free survival; NLR, neutrophil-lymphocyte ratio; OS, overall survival; PLR, platelet-lymphocyte ratio.

Figure 2 Kaplan–Meier curves of NLR and PLR for DFS and OS.Notes: (A) NLR for DFS, (B) PLR for DFS, (C) NLR for OS, (D) PLR for OS.Abbreviations: DFS, disease-free survival; NLR, neutrophil-lymphocyte ratio; OS, overall survival; PLR, platelet-lymphocyte ratio.

Table 4 Multivariate analyses for DFS and OS

Table 5 Multivariate analyses of NLR and PLR for DFS and OS stratified by pTNM stage

Figure 3 Nomograms and their accuracy for predicting 1-year DFS in patients with resectable PDAC.

Notes: (A) Nomogram including NLR and PLR, (B) nomogram without NLR and PLR, (C) bootstrap-corrected AUCs for model including NLR and PLR, (D) bootstrap-corrected (BS) AUCs for model without NLR and PLR.

Abbreviations: AUCs, areas under the curve; DFS, disease-free survival; ECOG PS, Eastern Cooperative Oncology Group performance status; NLR, neutrophil-lymphocyte ratio; PDAC, pancreatic ductal adenocarcinoma; PLR, platelet-lymphocyte ratio.

Figure 3 Nomograms and their accuracy for predicting 1-year DFS in patients with resectable PDAC.Notes: (A) Nomogram including NLR and PLR, (B) nomogram without NLR and PLR, (C) bootstrap-corrected AUCs for model including NLR and PLR, (D) bootstrap-corrected (BS) AUCs for model without NLR and PLR.Abbreviations: AUCs, areas under the curve; DFS, disease-free survival; ECOG PS, Eastern Cooperative Oncology Group performance status; NLR, neutrophil-lymphocyte ratio; PDAC, pancreatic ductal adenocarcinoma; PLR, platelet-lymphocyte ratio.