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Cancer Management and Research Volume 11, 2019 - Issue
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Review

Radiation-induced skin reactions: mechanism and treatment

Jinlong Wei1 Department of Radiation Oncology, The First Hospital of Jilin University, Changchun 130021, China, [email protected]
,
Lingbin Meng2 Department of Internal Medicine, Florida Hospital, Orlando, FL 32803, USA
,
Xue Hou1 Department of Radiation Oncology, The First Hospital of Jilin University, Changchun 130021, China, [email protected]
,
Chao Qu1 Department of Radiation Oncology, The First Hospital of Jilin University, Changchun 130021, China, [email protected]
,
Bin Wang1 Department of Radiation Oncology, The First Hospital of Jilin University, Changchun 130021, China, [email protected]
,
Ying Xin3 Key Laboratory of Pathobiology, Ministry of Education, Jilin University, Changchun 130021, China, [email protected]Correspondence[email protected]
&
Xin Jiang1 Department of Radiation Oncology, The First Hospital of Jilin University, Changchun 130021, China, [email protected]Correspondence[email protected]
 show all
Pages 167-177 | Published online: 21 Dec 2018

Figures & data

Figure 1 Mechanisms associated with RISRs: inflammation and oxidative stress.

Abbreviations: COX-2, cyclooxygenase 2; ICAM-1, intercellular adhesion molecule 1; iNOS, inducible nitric oxide synthase; NF-kB, nuclear factor kB; NLRP3, nucleotide-binding domain, leucine-rich repeat-containing family, pyrin domain-containing 3; NO, nitric oxide; RISR, radiation-induced skin reaction; TNF, tumor necrosis factor; VCAM, vascular cell adhesion protein.

Figure 1 Mechanisms associated with RISRs: inflammation and oxidative stress.Abbreviations: COX-2, cyclooxygenase 2; ICAM-1, intercellular adhesion molecule 1; iNOS, inducible nitric oxide synthase; NF-kB, nuclear factor kB; NLRP3, nucleotide-binding domain, leucine-rich repeat-containing family, pyrin domain-containing 3; NO, nitric oxide; RISR, radiation-induced skin reaction; TNF, tumor necrosis factor; VCAM, vascular cell adhesion protein.

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