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Original Research

A sample model established by S-index predicting overall survival after curative resection of primary hepatocellular carcinoma

, , , , , , , & show all
Pages 693-703 | Published online: 14 Jan 2019

Figures & data

Table 1 Baseline demographics and clinical characteristics of patients in the training cohort and the validation cohort

Table 2 Univariate analysis of the training cohort

Table 3 Multivariate analysis of the training cohort

Figure 1 Nomogram for predicting overall survival after curative resection of PHCC.

Notes: To obtain the corresponding survival probability, sum up each variable score and draw a vertical line from the total points scale to the survival rate scale.

Abbreviations: ALB, albumin; PHCC, primary hepatocellular carcinoma; PVTT, portal vein tumor thrombus; TBil, total bilirubin.

Figure 1 Nomogram for predicting overall survival after curative resection of PHCC.Notes: To obtain the corresponding survival probability, sum up each variable score and draw a vertical line from the total points scale to the survival rate scale.Abbreviations: ALB, albumin; PHCC, primary hepatocellular carcinoma; PVTT, portal vein tumor thrombus; TBil, total bilirubin.

Figure 2 Calibration curves for predicting overall survival probability by the nomogram in the training and validation sets.

Notes: Calibration curves of the prognostic nomogram for 1-year overall survival (A), 3-year overall survival (B) and 5-year overall survival (C) in the training set, correspondingly, calibration curves for 1-year overall survival (D), 3-year overall survival (E), and 5-year overall survival (F) in the validation set.

Figure 2 Calibration curves for predicting overall survival probability by the nomogram in the training and validation sets.Notes: Calibration curves of the prognostic nomogram for 1-year overall survival (A), 3-year overall survival (B) and 5-year overall survival (C) in the training set, correspondingly, calibration curves for 1-year overall survival (D), 3-year overall survival (E), and 5-year overall survival (F) in the validation set.

Figure 3 The tdROC curve of the prognostic nomogram, S-index, CLIP, BCLC and Okuda score in the training cohort.

Note: The tdROC curve for 1-year survival (A), 3-year survival (B), and 5-year survival (C).

Abbreviations: BCLC, Barcelona Clinic Liver Cancer; CLIP, Cancer of the Liver Italian Program; tdROC, time-dependent receiver operating characteristic.

Figure 3 The tdROC curve of the prognostic nomogram, S-index, CLIP, BCLC and Okuda score in the training cohort.Note: The tdROC curve for 1-year survival (A), 3-year survival (B), and 5-year survival (C).Abbreviations: BCLC, Barcelona Clinic Liver Cancer; CLIP, Cancer of the Liver Italian Program; tdROC, time-dependent receiver operating characteristic.

Figure 4 Survival curves stratified by the score calculated by the nomogram in the training cohort (low risk: <200; intermediate risk: 200–250; and high risk: >250).

Figure 4 Survival curves stratified by the score calculated by the nomogram in the training cohort (low risk: <200; intermediate risk: 200–250; and high risk: >250).

Table 4 Nomogram scoring system

Figure S1 The tdROC curve for S-index.

Figure S1 The tdROC curve for S-index.

Table S1 The optimal cutoff value of S-index