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Original Research

Antibiotic therapy augments the efficacy of gemcitabine-containing regimens for advanced cancer: a retrospective study

, , , , , , , , , , & show all
Pages 7953-7965 | Published online: 22 Aug 2019

Figures & data

Table 1 Patient characteristics

Table 2 Response rate of gemcitabine-containing regimens

Figure 1 Kaplan–Meier curve of the PFS rate in the antibiotics-untreated group and antibiotics-treated group.

Abbreviation: PFS, progression-free survival.

Figure 1 Kaplan–Meier curve of the PFS rate in the antibiotics-untreated group and antibiotics-treated group.Abbreviation: PFS, progression-free survival.

Figure 2 Kaplan–Meier curve of the OS rate with the antibiotics-untreated group and antibiotics-treated group.

Abbreviation: OS, overall survival

Figure 2 Kaplan–Meier curve of the OS rate with the antibiotics-untreated group and antibiotics-treated group.Abbreviation: OS, overall survival

Table 3 Severe (grade 3 or 4) toxicities by gemcitabine-containing regimens

Table 4 Univariate and multivariate analyses for the relationship between the response to the gemcitabine-containing regimens and patients’ background or toxicity by gemcitabine-containing regimens

Table S1 The median progression free survival time (PFS) or the median OS of the patients with biliary tract cancer, pancreatic cancer, sarcoma and other cancers in antibiotics-untreated group and antibiotics-treated group

Table S2 Patient’s original data in the present study