Dynamic Changes Of Body Image And Quality Of Life In Breast Cancer Patients

Figures & data

Table 1 Demographic And Clinical Characteristics Of Breast Cancer Patients. (N=581)

	Breast-Conserving Surgery	Total Mastectomy	p
Total no. of patients	211	370
Age (year); Mean ± SD	52.3±8.8	53.7±9.2	0.06
≥55 y/o	79 (37.4%)	154 (41.6%)	0.32
Education≤ 6 years	29 (13.7%)	56 (15.1%)	0.93
7–12 years	93 (44.1%)	178 (48.1%)
> 12 years	86 (40.8%)	135 (36.5%)
Married or cohabited	156 (73.9%)	268 (72.4%)	0.70
Income^a >US$1646/month	129 (61.1%)	207 (56.9%)	0.32
Pathologic stage 0	25 (11.8%)	46 (12.4%)	<0.001
I	119 (56.4%)	97 (26.2%)
II	59 (28.0%)	163 (44.1%)
III	8 (3.8%)	64 (17.3%)
Lymph node dissection (-)	11 (5.2%)	11 (2.9%)	<0.001
Sentinel lymph node biopsy	142 (67.3%)	126 (34.1%)
Axillary lymph node dissection	58 (27.5%)	233 (63.0%)
Months after surgery(Mean±SD)	33.3±30.9	32.2±32.0	0.66
Within 1 year	75 (35.5%)	147 (39.7%)	0.24
1–5 years	96 (45.5%)	142 (38.4%)
>5 years	40 (19.0%)	81 (21.9%)
Chemotherapy: Never	90 (42.7%)	125 (33.8%)	0.07
≤6 months	20 (9.5%)	51 (13.8%)
>6 months	101 (47.8%)	194 (52.4%)
Radiotherapy: Never	51 (24.2%)	263 (71.1%)	<0.001
≤2 years	72 (34.1%)	47 (12.7%)
>2 years	88 (41.7%)	60 (16.2%)
Hormone therapy<10 years	143 (67.8%)	215 (58.1%)	0.02
Diabetes mellitus (yes)	13 (6.2%)	33 (8.9%)	0.22
Heart Disease (yes)	6 (2.8%)	9 (2.4%)	0.76
Total independence in activity of daily living	187 (95.4%)	319 (91.1%)	0.18
Body image scale (10–36)	13.6 ± 4.9	14.8 ± 5.3	0.01

Note: ^aFamily income.

Figure 1 Dynamic changes of scores of the Body Image Scale in patients with breast cancer stratified by types of surgery and lymph node dissection.

Figure 2 Dynamic changes of scores of the WHOQOL-BREF in patients with breast cancer according to the surgery type.

Table 2 Regression Coefficients Of Each Domain And Item Scores Of The WHOQOL-BREF Based On Multiple Linear Regression Models; Those With No Statistical Significance (P> 0.05) Were Not Listed

Item	No Lymph Node Dissection vs Axillary Lymph Node Dissection	Breast-Conserving Surgery & No Lymph Node Dissection vs Total Mastectomy & Axillary Lymph Node Dissection	Chemotherapy ≤6 mo vs Chemotherapy (−)	Chemotherapy > 6 mo vs Chemotherapy (−)	Chemotherapy > 6 mo & Radiotherapy Within 2 Years vs Chemotherapy (−) & Radiotherapy (−)	Body Image	Dependence In Activity Of Daily Living
-Physical Domain			−0.76(0.32)	−0.61(0.28)	1.32(0.52)	−0.16(0.02)	−1.31(0.33)
Medication				−0.30(0.14)	0.57(0.25)	−0.02(0.01)
Sleep and rest			−0.56(0.16)	−0.32(0.14)	0.75(0.25)	−0.06(0.01)
Psychological Domain							-1.19(0.38)
Positive feelings	−0.90(0.30)					−0.05(0.01)	−0.48(0.16)
Body image			−0.32(0.13)			−0.09(0.01)
Negative feeling						−0.06(0.01)
Social Domain
Sexual activity	0.52(0.23)					−0.04(0.01)
Social support						−0.03(0)
Environment Domain				−0.76(0.27)		−0.11(0.02)	−0.80(0.32)
Safety and security		0.85(0.38)				−0.06(0.01)
Financial resources				−0.37(0.13)		−0.04(0.01)
Leisure activities		−1.03(0.48)				−0.02(0.01)	−0.72(0.17)
Health services			−0.18(0.09)	−0.22(0.08)		−0.02(0.00)	−0.26(0.1)
Overall QoL	−0.49(0.23)					−0.04(0.01)	−0.31(0.12)

Notes: All models have controlled following confounders: age, age groups (>55/<55 years old), hormone therapy (yes/no), marital status (yes/no), 3 education levels, and family income (>/<USD $1650/month), co-morbidities, pathological stage, types of lymph node dissection (sentinel lymph node biopsy/(-)), and axillary lymph node dissection/(-)), time after first chemotherapy (>18/<18 months), time after first radiotherapy (>13/<13 months), time after surgery (<1/1–5/>5 years), and interactions of types of surgery and lymph node dissection.

Abbreviations: Chemotherapy (-), never chemotherapy; Chemotherapy ≤6 mo, within 6 months after the first chemotherapy; Chemotherapy >6 mo, beyond 6 months after the first chemotherapy; QoL, quality of life; Radiotherapy (-), never radiotherapy; Dependence in Dependence of activity of daily living, the score of the Barthel Index < 100.