Gastric Cancer Screening Methods: A Comparative Study of Two Scoring Methods

Figures & data

Table 1 Novel Scoring System for Gastric Cancer Screening

Variates	Classification	Score
Age (years)	40 ~ 49	0
	50 ~ 9	5
	60 ~ 69	6
	>69	10
Gender	Female	0
	Male	4
Helicobacter pylori antibody	Negative	0
	Positive	1
Serum pepsinogen I/II ratio	≥3.89	0
	<3.89	3
	<1.50	0
Gastrin 17 (pmol/L)	1.50 ~ 5.70	3
	>5.70	5

Table 2 Simplified Scoring Sheet for Risk Assessment of Gastric Cancer in 10 Years

Items	Score	Items	Score
Age (year)		Family history
40–44	Female 0 Male 1	No	0
45–49	Female 1 Male 3	Yes	1
50–54	Female 2 Male 4	ABC risk stratification
55–59	Female 3 Male 6	A	0
60–64	Female 4 Male 8	B	8
65–71	Female 5 Male 10	C	11
Smoking		D	11
Never before	0
Smoking now	1	Total score	0 −24
Eating salted caviar
No	0
Yes	1

Table 3 General Information of Participants (N=342)

Age (year)	40–74
Male/Female (case)	137: 205
Age (%)
40–50 [case number (%)]	53 (15.5)
51–60 [case number (%)]	104 (30.4)
>60 [case number (%)]	185 (54.1)
Smoking history
Yes [case number (%)]	46 (13.4)
Pickled food eating
Yes [case number (%)]	235 (68.7)
Family history of gastric cancer
Yes [case number (%)]	33 (11.3)
Exhale test
Positive [case number (%)]	151 (44.2)
Helicobacter pylori antibody
Yes [case number (%)]	92 (26.9)

Table 4 Comparison of Risk Stratification Results Between the Two Scoring Methods (Case %)

Scoring Method	Case Number	Risk Stratification
		Low Risk	Medium Risk	High Risk
Japanese scoring	342	313 (91.52)	27 (7.89)	2 (0.58)
Li’ Scoring	342	264 (77.19)	75 (21.93)	3 (0.88)

Table 5 Novel Scoring System for Gastric Cancer Screening

Li’s Scoring			Japanese Scoring
Cut-Off Point	Sensitivity	Specificity	Cut-Off Point	Sensitivity	Specificity
9.5	0.818	0.577	9.5	0.727	0.619
10.5	0.818	0.69	10.5	0.545	0.687
11.5	0.727	0.751	11.5	0.545	0.74
12.5	0.636	0.769	12.5	0.545	0.811
13.5	0.636	0.911	13.5	0.545	0.875
14.5	0.455	0.954	14.5	0.455	0.915
15.5	0.364	0.979	15.5	0.455	0.929

Figure 1 Shows the ROC curve analysis of two scoring methods to diagnose early gastric cancer.