Figures & data
Figure 1 Analysis of TCGA database. (A) The database erases the volcanic map of the genes that differ from the normal sample. (B) Determination of soft threshold (β) for weighted gene co-expression network analysis. (C) Gene cluster dendrogram. (D) Heat map of correlation between clinical features and module features. (E) Go histogram of co-expression differential genes. (F) KEGG histogram of co-expression differential genes.
![Figure 1 Analysis of TCGA database. (A) The database erases the volcanic map of the genes that differ from the normal sample. (B) Determination of soft threshold (β) for weighted gene co-expression network analysis. (C) Gene cluster dendrogram. (D) Heat map of correlation between clinical features and module features. (E) Go histogram of co-expression differential genes. (F) KEGG histogram of co-expression differential genes.](/cms/asset/90fccc0a-03b8-4590-a971-1c03249f2db3/dcmr_a_12189785_f0001_c.jpg)
Figure 2 VENN. (A) DEGs of the most significant down-regulated module in the TCGA database. (B) DEGs of the most significant down-regulated module in the TCGA database. (C) DEGs of the most significant down-regulated module in the TCGA database. (D) DEGs were co-expressed in three databases.
![Figure 2 VENN. (A) DEGs of the most significant down-regulated module in the TCGA database. (B) DEGs of the most significant down-regulated module in the TCGA database. (C) DEGs of the most significant down-regulated module in the TCGA database. (D) DEGs were co-expressed in three databases.](/cms/asset/e15770ca-0c8a-46ac-b4d9-3ebad6f6c505/dcmr_a_12189785_f0002_c.jpg)
Figure 3 Analysis of GEO database: (A–F) Analysis of GSE106582 database (The figures type are the same as database TCGA). (G–L) Analysis of GSE110224 database (The figures type are the same as database TCGA).
![Figure 3 Analysis of GEO database: (A–F) Analysis of GSE106582 database (The figures type are the same as database TCGA). (G–L) Analysis of GSE110224 database (The figures type are the same as database TCGA).](/cms/asset/828a8d1e-2b66-4c7b-aa5a-f20394684601/dcmr_a_12189785_f0003_c.jpg)
Figure 4 (A–D) The survival curves of continuous variables of key genes. (E–L) Scatter plots and paired plots of gene expression differences of key genes.
![Figure 4 (A–D) The survival curves of continuous variables of key genes. (E–L) Scatter plots and paired plots of gene expression differences of key genes.](/cms/asset/ae9cc435-00ec-41e3-b2fb-1fe24549615d/dcmr_a_12189785_f0004_c.jpg)
Figure 5 (A) Correlation between VSIG2 and immune cells. (B) Correlation of VSIG2 with tumor-associated M1 macrophage markers. (C) correlation of VSIG2 with tumor-associated M2 macrophage markers.
![Figure 5 (A) Correlation between VSIG2 and immune cells. (B) Correlation of VSIG2 with tumor-associated M1 macrophage markers. (C) correlation of VSIG2 with tumor-associated M2 macrophage markers.](/cms/asset/33682702-053c-414e-a910-4416bc088de9/dcmr_a_12189785_f0005_c.jpg)
Table 1 Expression of VSIG2 in Immune Cells of Cancer and Normal Tissues
Figure 6 (A) The expression of VSIG2 in normal tissues. (B) The expression of VSIG2 in cancer tissues. (C) The expression of LC3 in cancer tissues.
![Figure 6 (A) The expression of VSIG2 in normal tissues. (B) The expression of VSIG2 in cancer tissues. (C) The expression of LC3 in cancer tissues.](/cms/asset/12e435f7-77c0-4b3e-979d-fb9ff43211c0/dcmr_a_12189785_f0006_c.jpg)
Table 2 Correlation Between the Expression of VSIG2 in Immune Cells of Cancer Tissue and the Intensity of Immune Invasion
Table 3 Correlation Between Autophagy - Related Factor LC3 and the Intensity of Immune Invasion in Cancer Tissue
Table 4 Correlation Between the Expression of LC3 and VSIG2 and the Intensity of Immune Invasion