https://orcid.org/0000-0002-7596-8011
Figures & data
Table 1 Classification of circRNAs
Figure 1 Biogenesis of circRNAs. (A) CircRNAs are mainly produced by three mechanisms: lariat-driven, intron-pairing-driven, RNA-binding proteins (RBPs)-driven circularization. (B) Inter-genic circRNAs are spliced by two intronic circRNA fragments containing GT-AG splicing signals. (C) TricRNAs are produced from pre-tRNAs that containing introns.
Figure 2 Function of circRNAs. (A) miRNA sponge (B) Translation regulator (C) Protein translation (D) Protein sponge (E) RNA maturation (F) Inhibit RNA polymerase II elongation (G) Modulate linear splicing.
Table 2 CircRNAs as Potential Diagnostic Biomarkers in Lung Cancer
Table 3 CircRNAs as Potential Prognostic Biomarkers in Lung Cancer
Table 4 CircRNAs as Potential Therapeutic Target in Lung Cancer