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Cancer Management and Research Volume 13, 2021 - Issue
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Study Protocol

Phase II Study of Nivolumab Plus Ipilimumab with Platinum-Based Chemotherapy for Treatment-Naïve Advanced Non-Small Cell Lung Cancer with Untreated Brain Metastases: NIke Trial (LOGiK2004)

Yuko Tsuchiya-Kawano1 Department of Respiratory Medicine, Kitakyushu Municipal Medical Center, Kitakyushu, Japan
,
Yoshimasa Shiraishi2 Research Institute for Diseases of the Chest, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
,
Fumiaki Kiyomi3 Statistics and Data Center, Clinical Research Support Center Kyushu, Fukuoka, JapanORCID Iconhttps://orcid.org/0000-0002-1001-3513
ORCID Icon &
Isamu Okamoto2 Research Institute for Diseases of the Chest, Graduate School of Medical Sciences, Kyushu University, Fukuoka, JapanCorrespondence[email protected]
Pages 8489-8493 | Published online: 11 Nov 2021

Figures & data

Figure 1 Design of the NIke Trial.

Abbreviations: NSCLC, non-small cell lung cancer; ECOG PS, Eastern Cooperative Oncology Group performance status; MRI, magnetic resonance imaging; PD, progressive disease; PFS, progression-free survival; ORR, objective response rate; OS, overall survival.
Figure 1 Design of the NIke Trial.

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