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ORIGINAL RESEARCH

The Combination of Anlotinib and Gemcitabine/Docetaxel in Patients with Metastatic Osteosarcoma Who Have Failed Standard Chemotherapy

ORCID Icon, , , , , , , ORCID Icon & show all
Pages 2945-2952 | Received 19 Jun 2022, Accepted 13 Sep 2022, Published online: 27 Nov 2023

Figures & data

Table 1 Baseline Characteristics

Figure 1 Kaplan–Meier plot of progression-free survival (PFS). Blue line: PFS for patients in the GD group (gemcitabine/docetaxel). Red line: PFS for patients in the combination group (anlotinib and gemcitabine/docetaxel).

Figure 1 Kaplan–Meier plot of progression-free survival (PFS). Blue line: PFS for patients in the GD group (gemcitabine/docetaxel). Red line: PFS for patients in the combination group (anlotinib and gemcitabine/docetaxel).

Table 2 Treatment Response of the Two Groups

Figure 2 Best percentage change in target lesion size of patients. (The dashed lines represent the criteria for progressive disease (20% increase in target lesion size) and partial response (30% decrease in target lesion size) according to RECIST v1.1).

Figure 2 Best percentage change in target lesion size of patients. (The dashed lines represent the criteria for progressive disease (20% increase in target lesion size) and partial response (30% decrease in target lesion size) according to RECIST v1.1).

Table 3 The Most Common Adverse Events in the Two Groups