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CASE SERIES

Extensive Stage Small-Cell Lung Cancer with Cystic Brain Metastases: A Report of Two Cases

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Pages 177-183 | Received 14 Nov 2023, Accepted 12 Mar 2024, Published online: 18 Mar 2024

Figures & data

Figure 1 Baseline before immunotherapy. (A) 2 cycles after immunotherapy. (B) November 2021, cystic brain metastasis. (C) February 2022, 3 months after cystic brain metastasis. (D) February 2022, chest CT after radiotherapy for brain lesions. (E) May 2022, chest CT of recurrence of the right hilar of the right lung nodules. (F) November 2022, 1 year after cystic brain metastasis. (G).

Figure 1 Baseline before immunotherapy. (A) 2 cycles after immunotherapy. (B) November 2021, cystic brain metastasis. (C) February 2022, 3 months after cystic brain metastasis. (D) February 2022, chest CT after radiotherapy for brain lesions. (E) May 2022, chest CT of recurrence of the right hilar of the right lung nodules. (F) November 2022, 1 year after cystic brain metastasis. (G).

Figure 2 HE staining of primary lesion (ES-SCLC) in the first patient (AD).

Figure 2 HE staining of primary lesion (ES-SCLC) in the first patient (A–D).

Figure 3 Baseline before immunotherapy. (A) 4 cycles after immunotherapy. (B) February 2021, chest CT before cystic brain metastasis. (C) March 2021, cystic brain metastasis. (D) April 2021, chest CT SD. (E) September 2021; 6 months after cystic brain metastases occurred. (F) March 2022, spinal metastasis. (G).

Figure 3 Baseline before immunotherapy. (A) 4 cycles after immunotherapy. (B) February 2021, chest CT before cystic brain metastasis. (C) March 2021, cystic brain metastasis. (D) April 2021, chest CT SD. (E) September 2021; 6 months after cystic brain metastases occurred. (F) March 2022, spinal metastasis. (G).

Figure 4 HE staining of primary lesion (ES-SCLC0 in the second patient (AD).

Figure 4 HE staining of primary lesion (ES-SCLC0 in the second patient (A–D).