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ORIGINAL RESEARCH

Development and Validation of a Prognostic Nomogram for HR+ HER- Breast Cancer

ORCID Icon, , , ORCID Icon, ORCID Icon &
Pages 491-505 | Received 15 Jan 2024, Accepted 08 May 2024, Published online: 20 May 2024

Figures & data

Table 1 Clinicopathological Characteristics of the Training and Validation Groups

Figure 1 Patient selection flowchart.

Figure 1 Patient selection flowchart.

Table 2 Univariate and Multivariate Analyses of DFS in the Training Group

Figure 2 Nomogram for the prediction of DFS in HR+ HER2- breast cancer.

Abbreviations: PLR, platelet to lymphocyte count ratio; DFS, disease free survival.
Figure 2 Nomogram for the prediction of DFS in HR+ HER2- breast cancer.

Figure 3 Calibration curves for predicting the DFS for patients with HR+ HER2- breast cancer in the training group at (A) 5 years and (B) 8 years and in the validation group at (C) 5 years and (D) 8 years. Nomogram-predicted probability is plotted on the x-axis and the actual survival is plotted on the y-axis.

Abbreviation: DFS, disease-free survival.
Figure 3 Calibration curves for predicting the DFS for patients with HR+ HER2- breast cancer in the training group at (A) 5 years and (B) 8 years and in the validation group at (C) 5 years and (D) 8 years. Nomogram-predicted probability is plotted on the x-axis and the actual survival is plotted on the y-axis.

Figure 4 5 years (A) and 8 years (B) ROC curves for DFS.

Abbreviation: DFS, disease-free survival.
Figure 4 5 years (A) and 8 years (B) ROC curves for DFS.

Table 3 Univariate Analyses of DFS by Total DFS Score

Figure 5 Risk group stratification in the total, training and validation group. DFS curves of patients in the total group (A), training group (B) and validation group (C) by nomogram score groups.

Abbreviation: DFS, disease-free survival.
Figure 5 Risk group stratification in the total, training and validation group. DFS curves of patients in the total group (A), training group (B) and validation group (C) by nomogram score groups.

Table 4 Univariate Analyses of DFS in Different Risk Groups by Postoperative Adjuvant Chemotherapy

Figure 6 Risk group stratification in the low risk, medium risk, high risk and total group. DFS curves of patients in the low risk group (A), medium risk group (B), high risk group (C) and total group (D) by different postoperative adjuvant chemotherapy strategy.

Abbreviation: DFS, disease-free survival.
Figure 6 Risk group stratification in the low risk, medium risk, high risk and total group. DFS curves of patients in the low risk group (A), medium risk group (B), high risk group (C) and total group (D) by different postoperative adjuvant chemotherapy strategy.