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Original Research

Long-acting bronchodilators with or without inhaled corticosteroids and 30-day readmission in patients hospitalized for COPD

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Pages 477-486 | Published online: 31 Jan 2017

Figures & data

Figure 1 Establishment of study cohort.

Abbreviations: ICD, International Classification of Diseases; ICD-9, ICD, Ninth Revision; LABDs, long-acting bronchodilators; ICSs, inhaled corticosteroids; Jan, January; Dec, December; SNF, skilled nursing facility.
Figure 1 Establishment of study cohort.

Figure 2 Prescription for long-acting bronchodilators, with or without ICSs, filled by patients with COPD 90 days prior to index hospitalization to 30 days after the discharge in 2011.

Abbreviation: ICSs, inhaled corticosteroids.
Figure 2 Prescription for long-acting bronchodilators, with or without ICSs, filled by patients with COPD 90 days prior to index hospitalization to 30 days after the discharge in 2011.

Table 1 Baseline characteristics of LABDs with or without ICSs user and nonuser patients hospitalized with COPD in 2011

Table 2 Health-care utilization within 30 days of discharge by LABDs±ICSs with or without LABDs±ICSs users and nonusers groups

Figure 3 Propensity score distribution plot comparing LABDs±ICSs users vs nonusers before and after matching.

Notes: Propensity score matching adjusting for age, gender, race, region, Medicaid eligibility, comorbidity score, number of hospital beds, medical school affiliation, type of hospital, type of admission, hospitalization 1 year before index hospitalization, ICU/CCU during index hospitalization, MV during index hospitalization, oxygen therapy 1 year before index hospitalization, pulmonary specialist visit 1 year before index hospitalization, length of index hospitalization stay and pulmonary specialist visit during index hospitalization.

Abbreviations: LABDs, long-acting bronchodilators; ICSs, inhaled corticosteroids; ICU, intensive care unit; CCU, coronary care unit; MV, mechanical ventilation.

Figure 3 Propensity score distribution plot comparing LABDs±ICSs users vs nonusers before and after matching.Notes: Propensity score matching adjusting for age, gender, race, region, Medicaid eligibility, comorbidity score, number of hospital beds, medical school affiliation, type of hospital, type of admission, hospitalization 1 year before index hospitalization, ICU/CCU during index hospitalization, MV during index hospitalization, oxygen therapy 1 year before index hospitalization, pulmonary specialist visit 1 year before index hospitalization, length of index hospitalization stay and pulmonary specialist visit during index hospitalization.Abbreviations: LABDs, long-acting bronchodilators; ICSs, inhaled corticosteroids; ICU, intensive care unit; CCU, coronary care unit; MV, mechanical ventilation.

Figure 4 Odds of ER visit and readmission within 30 days after index hospitalization related to COPD in patients using LABDs±ICSs 90 days prior to hospitalization and/or 30 days after discharge.

Notes: *Matched: propensity score matching adjusted for age, gender, race, region, Medicaid eligibility, comorbidity score, number of hospital beds, medical school affiliation, type of hospital, type of admission, hospitalization 1 year before index hospitalization, ICU/CCU during index hospitalization, MV during index hospitalization, oxygen therapy 1 year before index hospitalization, pulmonary specialist visit 1 year before index hospitalization, length of index hospitalization stay and pulmonary specialist visit during index hospitalization.
Abbreviations: LABDs, long-acting bronchodilators; ICSs, inhaled corticosteroids; ICU, intensive care unit; CCU, coronary care unit; ER, emergency room; MV, mechanical ventilation.
Figure 4 Odds of ER visit and readmission within 30 days after index hospitalization related to COPD in patients using LABDs±ICSs 90 days prior to hospitalization and/or 30 days after discharge.

Table S1 Health-care utilization within 30 days of discharge by LABDs with or without ICSs users and nonusers group for AECOPDTable Footnotea, N=3,925

Table S2 Health-care utilization within 30 days of discharge by LABDs with or without ICSs users and nonusers group after propensity matching, N=4,428