Figures & data
Table 1 Demographics and clinical characteristics of cohort
Figure 1 Prevalence of comorbidities by disease categories.
Table 2 Summary of MRCI and medication count for study population
Figure 2 Donut chart showing the percentage contributions of dosage form, dosing frequency, and additional instructions to the total MRCI scores of COPD, non-COPD, and all medications.
Figure 3 Summary of medication counts and MRCI scores of COPD, non-COPD, and all medications for study population based on GOLD quadrants.
Abbreviations: GOLD, Global Initiative for Chronic Obstructive Lung Disease; med, medication; MRCI, medication regimen complexity index.
Table 3 Correlations between clinical outcomes and medication burden
Table 4 Total medication counts and MRCI scores for all medications in patients with and without comorbidities
Figure 4 Medication regimen complexity in relation to class of comorbidities for non-COPD medications (A) and COPD medications (B).
Abbreviation: MRCI, medication regimen complexity index.
Table 5 Results of multiple regression analysis for comorbidities that contributed to higher medication count
Table 6 Results of multiple regression analysis for comorbidities that contributed to greater complexity of medication regimen
Table 7 Association of medication burden with comorbidity specific and multidimensional indices in COPD
Table S1 Prevalence of self-reported diagnosed comorbidities
Table S2 Use of nebulizer or oxygen in participants in different GOLD quadrants
Table S3 Medication counts and MRCI scores of COPD, non-COPD, and all medications in GOLD quadrants