Severe COPD cases from Korea, Poland, and USA have substantial differences in respiratory symptoms and other respiratory illnesses

Woo Jin Kim1 Department of Internal Medicine and Environmental Health Center, Kangwon National University Hospital, ChuncheonCorrespondence[email protected]

Jae-Joon Yim2 Department of Internal Medicine, Division of Pulmonary and Critical Care Medicine, Seoul National University College of Medicine, Seoul

Deog Kyeom Kim3 Department of Internal Medicine, Division of Pulmonary and Critical Care Medicine, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Seoul National University College of Medicine, Seoul

Myung Goo Lee4 Division of Pulmonary, Allergy and Critical Care Medicine, Hallym University Chuncheon Sacred Heart Hospital, Chuncheon, Korea

Anne L Fuhlbrigge5 Division of Pulmonary Sciences and Critical Care Medicine, University of Colorado School of Medicine, Aurora, CO, USA

Pawel Sliwinski6 2nd Department of Respiratory Medicine, Institute of Tuberculosis and Lung Diseases, Warsaw, Poland

Iwona Hawrylkiewicz6 2nd Department of Respiratory Medicine, Institute of Tuberculosis and Lung Diseases, Warsaw, Poland

Emily S Wan7 Channing Division of Network Medicine;8 Division of Pulmonary and Critical Care Medicine, Brigham and Women’s Hospital, Boston, MA, USA

Michael H Cho7 Channing Division of Network Medicine;8 Division of Pulmonary and Critical Care Medicine, Brigham and Women’s Hospital, Boston, MA, USA

Edwin K Silverman7 Channing Division of Network Medicine;8 Division of Pulmonary and Critical Care Medicine, Brigham and Women’s Hospital, Boston, MA, USACorrespondence[email protected]

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Severe COPD cases from Korea, Poland, and USA have substantial differences in respiratory symptoms and other respiratory illnesses

Table 1 Demographic and spirometric characteristics of severe COPD subjects from three countries (N [%] or mean ± standard deviation)

Table 2 Respiratory symptoms, respiratory illnesses, and environmental exposures in severe COPD subjects according to country (N [%] or mean ± standard deviation)

Table 3 Stratified comparison of respiratory symptoms, respiratory illnesses, and environmental exposures between countries in GOLD spirometry grade 3 (severe COPD) versus 4 (very severe COPD) (N [%] or mean ± standard deviation)

Table 4 Comparison of respiratory illnesses and environmental exposures in severe COPD cases and controls from Poland and Korea (N [%] or mean ± standard deviation)

Table 5 Multivariate models for respiratory symptoms among severe COPD cases in different countries

Table 6 Multivariate models for respiratory illnesses among severe COPD cases in different countries

Table S1 Respiratory symptoms, respiratory illnesses, and environmental exposures in only male severe COPD subjects according to country (N [%] or mean ± standard deviation)

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Severe COPD cases from Korea, Poland, and USA have substantial differences in respiratory symptoms and other respiratory illnesses

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Table 1 Demographic and spirometric characteristics of severe COPD subjects from three countries (N [%] or mean ± standard deviation)

Table 2 Respiratory symptoms, respiratory illnesses, and environmental exposures in severe COPD subjects according to country (N [%] or mean ± standard deviation)

Table 3 Stratified comparison of respiratory symptoms, respiratory illnesses, and environmental exposures between countries in GOLD spirometry grade 3 (severe COPD) versus 4 (very severe COPD) (N [%] or mean ± standard deviation)

Table 4 Comparison of respiratory illnesses and environmental exposures in severe COPD cases and controls from Poland and Korea (N [%] or mean ± standard deviation)

Table 5 Multivariate models for respiratory symptoms among severe COPD cases in different countries

Table 6 Multivariate models for respiratory illnesses among severe COPD cases in different countries

Table S1 Respiratory symptoms, respiratory illnesses, and environmental exposures in only male severe COPD subjects according to country (N [%] or mean ± standard deviation)

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