Figures & data
Table 1 Baseline characteristics of the study population in subgroups stratified by severity of lung function impairment
Figure 1 Receiver operating characteristic (ROC) curve showing the performance of FEV3 in evaluating bronchodilator test based on FVC evaluation criteria.
![Figure 1 Receiver operating characteristic (ROC) curve showing the performance of FEV3 in evaluating bronchodilator test based on FVC evaluation criteria.](/cms/asset/dc2ff209-bf27-481c-8ce9-dbd92bd598b5/dcop_a_197552_f0001_c.jpg)
Table 2 Characteristics of bronchodilator response in the study population
Table 3 Characteristics of post-bronchodilator response in subgroups stratified by level of lung function impairment
Figure 2 Frequency distribution of subjects in each group showing post-bronchodilator change in FEV1 of more than 12% of baseline but ≤200 mL in various subgroups stratified by level of lung function impairment.
![Figure 2 Frequency distribution of subjects in each group showing post-bronchodilator change in FEV1 of more than 12% of baseline but ≤200 mL in various subgroups stratified by level of lung function impairment.](/cms/asset/fbf95dd3-804e-4859-8670-93623b9d6979/dcop_a_197552_f0002_b.jpg)
Figure 3 Frequency distribution of subjects in each group whose post-bronchodilator responses become positive with ∆FVC response in various subgroups stratified by level of lung function impairment.
![Figure 3 Frequency distribution of subjects in each group whose post-bronchodilator responses become positive with ∆FVC response in various subgroups stratified by level of lung function impairment.](/cms/asset/328a57ac-dad9-4a8f-8e60-34de8c14d2c5/dcop_a_197552_f0003_b.jpg)
Figure 4 Frequency distribution of subjects in each group whose post-bronchodilator responses become positive with ∆FEV3 response in various subgroups stratified by level of lung function impairment.
![Figure 4 Frequency distribution of subjects in each group whose post-bronchodilator responses become positive with ∆FEV3 response in various subgroups stratified by level of lung function impairment.](/cms/asset/f0f37503-2694-4088-b4c3-538001ac8253/dcop_a_197552_f0004_b.jpg)
Table 4 Spirometric Indexes expressed as change post-bronchodilator and z scores in subgroups stratified by level of lung function impairment
Table 5 Spirometric Indexes in male subjects expressed as change in post-bronchodilator and z scores in subgroups stratified by level of lung function impairment
Table 6 Spirometric Indexes in female subjects expressed as change in post-bronchodilator and z-scores in subgroups stratified by level of lung function impairment
Figure 5 Post-bronchodilator change in z score of FEV1 (left) is larger in 70% pred≤FEV1<80% pred group, 60% pred≤FEV1<70% pred group and 50% pred≤FEV1<60% pred group compared with FEV1≥80% pred group and declines as obstruction becomes most severe. Conversely, the post-bronchodilator effect on FVC (middle) increased with the severity of lung function impairment. The patterns for FEV3 and FVC are similar. Thin lines, 5th and 95th percentiles; central thick line, median.
![Figure 5 Post-bronchodilator change in z score of FEV1 (left) is larger in 70% pred≤FEV1<80% pred group, 60% pred≤FEV1<70% pred group and 50% pred≤FEV1<60% pred group compared with FEV1≥80% pred group and declines as obstruction becomes most severe. Conversely, the post-bronchodilator effect on FVC (middle) increased with the severity of lung function impairment. The patterns for FEV3 and FVC are similar. Thin lines, 5th and 95th percentiles; central thick line, median.](/cms/asset/4b785d5a-7f5b-49bd-9768-984d753a32d8/dcop_a_197552_f0005_b.jpg)