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Original Research

External Validation Of The Updated ADO Score In COPD Patients From The Birmingham COPD Cohort

Spencer J Keene1 Institute of Applied Health Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK;2 Department of Clinical Pharmacy & Toxicology, Maastricht University Medical Center+, Maastricht, the Netherlands;3 Ciro, Horn, the Netherlands

https://orcid.org/0000-0003-0622-6476

Rachel E Jordan1 Institute of Applied Health Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UKCorrespondence[email protected]

Frits ME Franssen3 Ciro, Horn, the Netherlands;4 Department of Respiratory Medicine, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University Medical Centre+, Maastricht, The Netherlands

https://orcid.org/0000-0002-1633-6356

Frank de Vries2 Department of Clinical Pharmacy & Toxicology, Maastricht University Medical Center+, Maastricht, the Netherlands;5 Utrecht Institute for Pharmaceutical Sciences Utrecht University, Utrecht, The Netherlands

James Martin1 Institute of Applied Health Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK

Alice Sitch1 Institute of Applied Health Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK;6 NIHR Birmingham Biomedical Research Centre, University Hospitals Birmingham NHS Foundation Trust and University of Birmingham, Birmingham, UK

Alice Margaret Turner1 Institute of Applied Health Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK

Andrew P Dickens1 Institute of Applied Health Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK

https://orcid.org/0000-0002-7591-8129

David Fitzmaurice7 Clinical Trials Unit, Warwick Medical School, University of Warwick, Coventry, UK

Peymane Adab1 Institute of Applied Health Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK

https://orcid.org/0000-0001-9087-3945

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Figures & data

Figure 1 Patient (i.e. case) flow chart from whole cohort to ADO validation sample.

Table 1 Comparison Of Baseline Characteristics Of Existing COPD Cases With Those Who Were Screen Detected (N=1701)

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Table 2 Baseline Characteristics Of Cases (N=1701) By Whether Or Not They Died Within 3 Years Of Observation Time

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Figure 2 Kaplan–Meier plot of survival experience of patients by ADO score group at baseline. ADO score 0 to 5 used as the reference group (N= 1701).

Figure 3 Area-under-the-curve and calibration plots comparing observed and predicted mortality for incident and prevalent cases.

Data Availability

STATA code used for data manipulation and analyses can be provided upon request.

External Validation Of The Updated ADO Score In COPD Patients From The Birmingham COPD Cohort

Table 1 Comparison Of Baseline Characteristics Of Existing COPD Cases With Those Who Were Screen Detected (N=1701)

Table 2 Baseline Characteristics Of Cases (N=1701) By Whether Or Not They Died Within 3 Years Of Observation Time

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External Validation Of The Updated ADO Score In COPD Patients From The Birmingham COPD Cohort

Figures & data

Table 1 Comparison Of Baseline Characteristics Of Existing COPD Cases With Those Who Were Screen Detected (N=1701)

Table 2 Baseline Characteristics Of Cases (N=1701) By Whether Or Not They Died Within 3 Years Of Observation Time

Data Availability

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