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Original Research

A Comparison of the Real-Life Clinical Effectiveness of the Leading Licensed ICS/LABA Combination Inhalers in the Treatment for COPD

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Pages 3093-3103 | Published online: 26 Nov 2020

Figures & data

Figure 1 Study design.

Abbreviations: COPD, chronic obstructive pulmonary disease; FEV1, forced expiratory volume in 1 second; BDP/FF, beclometasone and formoterol fixed-dose combination inhaler; FP/SAL, fluticasone propionate and salmeterol fixed-dosed combination inhaler; BUD/FF, budesonide and formoterol fixed-dose combination inhaler.
Figure 1 Study design.

Table 1 Patient Flow and Inclusion and Exclusion Criteria

Table 2 Matched Baseline Patient Characteristics

Figure 2 Odds ratios for COPD exacerbation between BDP/FF and FP/SAL or BUD/FF.

Notes:aAdjusted for baseline ICS/LABA combination-inhaler prescriptions, baseline SABA prescriptions, baseline SAMA/SABA prescriptions, and active anxiety/depression. bAdjusted for theophylline prescription, ischemic heart disease diagnosis, and LTRA prescriptions. cAdjusted for SABA daily dose, ICS prescriptions, hypertension, and diabetes diagnosis.
Abbreviations: POP, population size; OR odds ratio; LCL, lower confidence interval; UCL, upper confidence interval.
Figure 2 Odds ratios for COPD exacerbation between BDP/FF and FP/SAL or BUD/FF.