Application Value of Broadband 3-Dimensional Impulse Oscillometry in COPD

Figures & data

Table 1 Basic Information of Research Object

	Control	Grade I	Grade II	Grade III	Grade IV
Cases	61	16	58	28	5
Gender (F/M)	20/41	4/12	21/37	6/22	0/5
Age (years)	65.71±11.10	65.38±8.12	70.83±8.91	71.79±9.47	68.20±5.54
Height (cm)	165.87±7.58	168.63±6.98	165.95±7.76	166.50±7.82	170.80±2.59
Weight (kg)	64.98±10.89	68.13±9.47	61.82±9.81	62.61±11.30	57.60±5.94
BMI (kg/m^2)	23.51±2.94	24.04±2.86	22.40±2.99	22.35±3.63	19.74±2.00

Table 2 Traditional Lung Function Parameters in COPD Group and Control Group

Group	FVC%pred	FEV1%pred	FEV1/FVC (%)
Control	91.9±13.84	101.64±15.52	87.20±6.93
COPD	73.74±19.68*	59.87±18.99*	59.19±8.28*

Note: *P<0.05, statistically significant.

Table 3 3D-IOS Parameters in COPD Group and Control Group

Group	R5	R20	R5–R20	X5	Fres
Control	3.71±1.54	2.94±1.27	0.77±0.51	−0.90±0.77	8.58±3.20
COPD	5.76±2.41*	4.29±1.73*	1.46±0.86*	−3.50±2.42*	15.53±4.17*

Note: *P<0.05, statistically significant.

Table 4 Comparison of Traditional Lung Function Parameters Among COPD Groups

GOLD Grade	FVC%pred	FEV1%pred	FEV1/FVC (%)
Grade I	91.90±13.84*	101.64±15.52*	87.20±6.93*
Grade II	76.68±13.00*	63.28±8.88*	60.99±6.49*
Grade III	57.91±10.63*	41.55±5.64*	53.27±6.72*
Grade IV	37.46±11.02*	23.66±5.24*	45.64±10.35*

Note: *P<0.05, statistically significant.

Table 5 Respiratory Resistance and Reactance Parameters Among COPD Groups

GOLD Grade	R5	R20	R5–R20	X5	Fres
Grade I	5.11±1.88*	3.87±1.54	1.24±0.54*	−1.96±1.15*	12.00±2.47*
Grade II	5.47±2.33*	4.08±1.66	1.38±0.83*	−3.04±2.21*	15.05±3.80*
Grade III	6.45±2.50*	4.81±1.81	1.64±0.87*	−4.81±2.40*	17.36±3.34*
Grade IV	7.36±3.46*	5.21±2.07	2.15±1.58*	−6.37±2.69*	22.03±5.37*

Note: *P<0.05, statistically significant among the groups.

Table 6 Correlation of Lung Function Parameters Between IOS and PFT in COPD Group

	R5	R20	R5–R20	X5	Fres
FVC%pred	−0.333*	−0.141	−0.403*	0.336**	−0.364**
FEV1%pred	−0.198*	−0.190	−0.339*	0.412**	−0.312*
FEV1/FVC	−0.317*	−0.113	−0.384*	0.278**	−0.467**

Note: *P<0.05, **P<0.01.

Figure 1 ROC of R5.

Figure 2 ROC of R5–R20.

Figure 3 ROC of X5.

Figure 4 ROC of Fres.

Figure 5 3D-colored images of COPD patient.

Figure 6 3D-colored images of healthy control.