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Original Research

Association of Chronic Obstructive Pulmonary Disease with Morbidity and Mortality in Patients with Peripheral Artery Disease: Insights from the EUCLID Trial

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Pages 841-851 | Published online: 29 Mar 2021

Figures & data

Figure 1 Inclusion criteria for EUCLID trial. This figure highlights the inclusion criteria of patients for both the EUCLID trial and this COPD-focused post hoc analysis of the EUCLID trial.

Figure 1 Inclusion criteria for EUCLID trial. This figure highlights the inclusion criteria of patients for both the EUCLID trial and this COPD-focused post hoc analysis of the EUCLID trial.

Table 1 Baseline Clinical Characteristics by COPD at Baseline

Figure 2 Kaplan–Meier plot of primary endpoint by history of COPD. The rate of occurrence of the primary endpoint (composite of cardiovascular death, myocardial infarction and ischemic stroke) is greater in patients with a history of COPD, compared to PAD patients without baseline COPD.

Figure 2 Kaplan–Meier plot of primary endpoint by history of COPD. The rate of occurrence of the primary endpoint (composite of cardiovascular death, myocardial infarction and ischemic stroke) is greater in patients with a history of COPD, compared to PAD patients without baseline COPD.

Table 2 Serious Adverse Events by History of COPD

Table 3 Adverse Events by History of COPD

Figure 3 Association between baseline COPD and clinical outcomes. This forest plot highlights the primary efficacy outcomes (MACE and MALE), secondary endpoints of interest (all-cause mortality), safety endpoints (TIMI major bleed), and serious adverse events (all-cause hospitalizations, hospitalization for dyspnea or pneumonia, premature study drug discontinuation).

Figure 3 Association between baseline COPD and clinical outcomes. This forest plot highlights the primary efficacy outcomes (MACE and MALE), secondary endpoints of interest (all-cause mortality), safety endpoints (TIMI major bleed), and serious adverse events (all-cause hospitalizations, hospitalization for dyspnea or pneumonia, premature study drug discontinuation).