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Original Research

A Novel Model-Based Questionnaire Based on Low-Dose CT Screening Data for Chronic Obstructive Pulmonary Disease Diagnosis in Shimane, Japan

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Pages 1823-1833 | Published online: 18 Jun 2021

Figures & data

Figure 1 Protocol for CT screening in Shimane, Japan.

Abbreviations: COPD, chronic obstructive pulmonary disease; CT, computed Tomography; HR-CT, high resolution computed tomography; FEV1, forced expiratory volume in one second; FVC, forced vital capacity.
Figure 1 Protocol for CT screening in Shimane, Japan.

Figure 2 Questionnaire created by our department and used for CT screening in Shimane, Japan. IPAG questionnaire items represent the interview questions that are the same as in the IPAG questionnaire.

Abbreviation: IPAG, International Primary Care Airways Group.
Figure 2 Questionnaire created by our department and used for CT screening in Shimane, Japan. IPAG questionnaire items represent the interview questions that are the same as in the IPAG questionnaire.

Table 1 Relationship Between Pack-Years and COPD Occurrence

Figure 3 ROC curve for pack-year (sample, n = 11,458). Area under ROC curve = 0.88588. A cut-off of 22.50 pack-year showed a sensitivity of 91.3% and a specificity of 73.0%.

Abbreviation: ROC, receiver operating characteristic.
Figure 3 ROC curve for pack-year (sample, n = 11,458). Area under ROC curve = 0.88588. A cut-off of 22.50 pack-year showed a sensitivity of 91.3% and a specificity of 73.0%.

Table 2 Baseline Characteristics of the Subjects and All Participants

Figure 4 ROC curve for the COPD questionnaire of IPAG (subset sample, n = 3252). Area under ROC curve = 0.67648. A cut-off score of 23.00 showed a sensitivity of 60.4% and a specificity of 63.8%.

Abbreviations: ROC, receiver operating characteristic; COPD, chronic obstructive pulmonary disease; IPAG, International Primary Care Airways Group.
Figure 4 ROC curve for the COPD questionnaire of IPAG (subset sample, n = 3252). Area under ROC curve = 0.67648. A cut-off score of 23.00 showed a sensitivity of 60.4% and a specificity of 63.8%.

Table 3 Efficacy of the Components of the Novel Questionnaire Used to Screen for COPD in Shimane, Japan

Table 4 COPD Predicted Value Calculated Using the Logistic Regression Model Obtained in This Study. It is Assumed That Responses to the Questions “Do You Often Develop Cough?”, “Do You Often Produce Sputum?”, and “Do You Often Have a Feeling of Dyspnea?” are All “Yes”

Table 5 COPD Predicted Value Calculated Using the Logistic Regression Model Obtained in This Study. It is Assumed That Response to the Questions “Do You Often Have a Feeling of Dyspnea?”, Which Has the Highest Odds Ratio Among the Narrowed Questionnaires, is “Yes”