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International Journal of Chronic Obstructive Pulmonary Disease Volume 16, 2021 - Issue
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Original Research

The Characteristics of Airflow Limitation and Future Exacerbations in Different GOLD Groups of COPD Patients

Qing Song1 Department of Respiratory and Critical Care Medicine, The Second Xiangya Hospital, Central South University, Changsha, Hunan, 410011, People’s Republic of China;2 Research Unit of Respiratory Disease, Central South University, Changsha, Hunan, 410011, People’s Republic of China;3 Diagnosis and Treatment Center of Respiratory Disease, Central South University, Changsha, Hunan, 410011, People’s Republic of ChinaView further author information
,
Yi-Yang Zhao1 Department of Respiratory and Critical Care Medicine, The Second Xiangya Hospital, Central South University, Changsha, Hunan, 410011, People’s Republic of China;2 Research Unit of Respiratory Disease, Central South University, Changsha, Hunan, 410011, People’s Republic of China;3 Diagnosis and Treatment Center of Respiratory Disease, Central South University, Changsha, Hunan, 410011, People’s Republic of ChinaORCID Iconhttps://orcid.org/0000-0001-5975-8025View further author information
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Yu-Qin Zeng1 Department of Respiratory and Critical Care Medicine, The Second Xiangya Hospital, Central South University, Changsha, Hunan, 410011, People’s Republic of China;2 Research Unit of Respiratory Disease, Central South University, Changsha, Hunan, 410011, People’s Republic of China;3 Diagnosis and Treatment Center of Respiratory Disease, Central South University, Changsha, Hunan, 410011, People’s Republic of ChinaView further author information
,
Cong Liu1 Department of Respiratory and Critical Care Medicine, The Second Xiangya Hospital, Central South University, Changsha, Hunan, 410011, People’s Republic of China;2 Research Unit of Respiratory Disease, Central South University, Changsha, Hunan, 410011, People’s Republic of China;3 Diagnosis and Treatment Center of Respiratory Disease, Central South University, Changsha, Hunan, 410011, People’s Republic of ChinaView further author information
,
Wei Cheng1 Department of Respiratory and Critical Care Medicine, The Second Xiangya Hospital, Central South University, Changsha, Hunan, 410011, People’s Republic of China;2 Research Unit of Respiratory Disease, Central South University, Changsha, Hunan, 410011, People’s Republic of China;3 Diagnosis and Treatment Center of Respiratory Disease, Central South University, Changsha, Hunan, 410011, People’s Republic of ChinaORCID Iconhttps://orcid.org/0000-0003-1025-0591View further author information
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Min-Hua Deng4 Department of Respiratory, PLA Rocket Force Characteristic Medical Center, Beijing, 100088, People’s Republic of ChinaORCID Iconhttps://orcid.org/0000-0002-2741-7266View further author information
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Xin Li5 Division 4 of Occupational Disease, Hunan Occupational Disease Prevention and Treatment Hospital, Changsha, Hunan, 410000, People’s Republic of ChinaORCID Iconhttps://orcid.org/0000-0002-5471-5808View further author information
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Li-Bing Ma6 Department of Respiratory and Critical Care Medicine, Affiliated Hospital of Guilin Medical University, Guilin, Guangxi, 541000, People’s Republic of ChinaView further author information
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Yan Chen1 Department of Respiratory and Critical Care Medicine, The Second Xiangya Hospital, Central South University, Changsha, Hunan, 410011, People’s Republic of China;2 Research Unit of Respiratory Disease, Central South University, Changsha, Hunan, 410011, People’s Republic of China;3 Diagnosis and Treatment Center of Respiratory Disease, Central South University, Changsha, Hunan, 410011, People’s Republic of ChinaView further author information
,
Shan Cai1 Department of Respiratory and Critical Care Medicine, The Second Xiangya Hospital, Central South University, Changsha, Hunan, 410011, People’s Republic of China;2 Research Unit of Respiratory Disease, Central South University, Changsha, Hunan, 410011, People’s Republic of China;3 Diagnosis and Treatment Center of Respiratory Disease, Central South University, Changsha, Hunan, 410011, People’s Republic of ChinaView further author information
&
Ping Chen1 Department of Respiratory and Critical Care Medicine, The Second Xiangya Hospital, Central South University, Changsha, Hunan, 410011, People’s Republic of China;2 Research Unit of Respiratory Disease, Central South University, Changsha, Hunan, 410011, People’s Republic of China;3 Diagnosis and Treatment Center of Respiratory Disease, Central South University, Changsha, Hunan, 410011, People’s Republic of ChinaCorrespondence[email protected]
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Pages 1401-1412 | Published online: 20 May 2021

Figures & data

Table 1 The Distribution of Baseline Demographic and Clinical Characteristics in Different Groups (N = 993)

Figure 1 Flow chart of study inclusion. Groups A to D were categories according to GOLD 2017 guidelines.

Abbreviations: COPD, chronic obstructive pulmonary disease; GOLD, Global Initiative for Chronic Obstructive Lung Disease; PFT, pulmonary function test.
Figure 1 Flow chart of study inclusion. Groups A to D were categories according to GOLD 2017 guidelines.

Table 2 Characteristics of Pulmonary Function in Different Groups (N = 993)

Table 3 Differences in Demographic and Clinical Characteristics for Different Severity of Airflow Limitation in Groups A, B, C and D (N = 993)

Table 4 Future Exacerbations and Mortality in Groups A, B, C and D After 18 Months of Follow-Up (N = 792)

Table 5 Future Exacerbations and Mortality for Different Severity of Airflow Limitation in Groups A, B, C and D After 18 Months of Follow-Up (N=792)

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