Predictive Value of Skeletal Muscle Function Test Combined with Climbing Test for Postoperative Cardiopulmonary Complications in Patients with COPD and Concurrent Lung Cancer

Figures & data

Table 1 Baseline Characteristics of the Study Population

	Complication Group (n=103)	Non Complication Group (n=232)	Χ^2/t	P
Age (years) ±SD	58.77±9.16	57.52±8.82	1.179	0.239
BMI (kg/m^2) ±SD	20.59±2.48	20.16±2.12	1.602	0.110
Quadriceps strength (kg) ±SD	10.06±2.96	17.75±5.56	−12.229	<0.001
Respiratory muscle strength (cmH2O) ±SD	19.83±8.65	27.02±10.06	−6.293	<0.001
6MWD (m) ±SD	140.00±48.13	173.66±49.51	−5.791	<0.001
Sex [n (%)]			0.543	0.461
Male	76 (31.9)	162 (68.1)
Female	27 (27.8)	70 (72.2)
Smoking history			11.626	0.001
Yes	73 (38.2)	118 (61.8)
No	30 (20.8)	114 (79.2)
History of Drinking			3.509	0.061
Yes	66 (27.7)	172 (72.3)
No	37 (38.1)	60 (61.9)
Climbing test			51.655	<0.001
Complete	66 (55.0)	54 (45.0)
Incomplete	37 (17.2)	178 (82.8)
DLCO%			13.575	<0.001
<60%	60 (41.4)	85 (58.6)
≥60%	43 (22.6)	147 (77.4)
FEV1%			47.406	<0.001
<60%	69 (52.3)	63 (47.7)
≥60%	34 (16.7)	169 (83.3)
ΔHR			19.634	<0.001
≥30 times /min	66 (42.9)	88 (57.1)
<30 times /min	37 (20.4)	144 (79.6)
ΔSpO2			75.739	<0.001
≥4%	81 (55.9)	64 (44.1)
<4%	22 (11.6)	168 (88.4)
Extent of resection			12.5541	<0.001
Lobes of lung	61 (40.7)	89 (59.3)
Sublobar lobe	42 (22.7)	143 (77.3)
Operation			79.978	<0.001
Thoracoscopic	55 (72.4)	21 (27.6)
VATS	48 (18.5)	211 (81.5)
Operative time			33.706	<0.001
≥210min	74 (46.0)	87 (54.0)
<210min	29 (16.7)	145 (83.3)
Blood loss			52.745	<0.001
≥100mL	63 (56.8)	48 (43.2)
<100mL	40 (17.9)	184 (82.1)

Note: Data are presented as the number of patients (%), mean ± SD.

Abbreviations: VATS, video-assisted thoracic surgery; SD, standard deviation; BMI, body mass index; FEV1, forced expiratory volume in one second; DLCO, carbon monoxide diffusing capacityΔHR, Heart rate changes before and after the test; ΔSpO2, Changes of finger pulse oxygen saturation before and after the test.

Table 2 Risk Factors for Postoperative Complications

	OR	95% CI	P
Respiratory muscle strength	1.077	1.032~1.123	0.001
Quadriceps strength	1.464	1.303~1.644	<0.001
Climbing test	6.334	2.550~15.738	<0.001
DLCO%	3.557	1.442~8.771	0.006
ΔSPO2	7.802	3.032~20.081	<0.001
Operation	5.873	2.212~15.609	<0.001
FEV1%	3.187	1.287~7.894	0.012

Abbreviations: FEV1, forced expiratory volume in one second; DLCO, carbon monoxide diffusing capacity; ΔSpO2, Changes of finger pulse oxygen saturation before and after the test.

Figure 1 The accuracy of the model for predicting the probability of postoperative complications was evaluated by use of the ROC curve.