Long-term evaluation of home-based pulmonary rehabilitation in patients with COPD

Figures & data

Figure 1 Flowchart showing participation throughout the study of the patients with COPD managed by home-based PR.

Abbreviation: PR, pulmonary rehabilitation.

Table 1 Baseline characteristics of the 211 patients who performed the PR program

Age (years)	62.3±11.1
Male, n (%)	143 (67.7)
BMI (kg/m^2)	26.8±7.3
FEV1 (% predicted)	41.5±17.7
FEV1/FVC (%)	50.4±12.8
Comorbidities, n (%)
0	3 (1.3)
1	26 (11.5)
2	26 (11.5)
≥3	171 (75.7)
Treatments, n (%)
Short-acting β2-agonists	132 (62.5)
Long-acting β2-agonists	95 (45)
Long-acting anticholinergic	158 (74.9)
Bronchodilator–corticosteroid combination	114 (54)
Inhaled corticosteroids	42 (19.9)
Oral corticosteroids	45 (21.3)
LTOT	77 (36.5)
LTOT + NIV	47 (22.3)
LTOT + CPAP	5 (2.4)
NIV	8 (3.8)
CPAP	12 (5.7)

Note: Data are expressed as mean ± standard deviation.

Abbreviations: PR, pulmonary rehabilitation; BMI, body mass index; FEV₁, mean forced expiratory volume in 1 second; FVC, forced vital capacity; LTOT, long-term oxygen therapy; NIV, noninvasive ventilation; CPAP, continuous positive airway pressure.

Table 2 Post hoc analyses comparing baseline, post-PR, 6 months and 12 months variables

	Baseline	Post-PR	6 months	12 months
n	211	195	171	159
6MST	328.9±163	394.7±172.6***	396.5±196.6***	432.6±182.1***
TUG	10.4±5.9	9 2±7.3**	9.6±5.6£	9.3±5.4
10TSTS	32.3±19.1	27.1±14.3***	28.1±14.3*	28.6±14
HAD	17.3±7.3	14.5±7.3***	13.2±7.1***,££	13.9±7.5***,§
MRF 28	48.5±23.4	39.6±23***	373±23.5***	39.5±25***,§
VQ11	33.4±9.1	29.7±9.9***	27.7±9***,££	29.4±10.3***,§
VSRQ	32.8±15.5	40.1±16.4***	41.6±15.7***	39.6±16.1***,§

Notes: Data are expressed as mean ± standard deviation.

* P<0.05,

** P<0.001,

*** P<0.0001, statistical comparison with baseline values;

£ P<0.05 and

££ P<0.01, statistical comparison with post-PR values;

§ P<0.05, statistical comparison with 6 months values. Data are presented as mean ± standard.

Abbreviations: PR, pulmonary rehabilitation; 6MST, 6-minute stepper test (number of steps); TUG, Timed Up and Go; 10TSTS, ten times sit-to-stand test; HAD, Hospital Anxiety and Depression questionnaire; MRF 28, Maugeri Respiratory Failure 28; VSRQ, Visual Simplified Respiratory Questionnaire.