Clinical Efficacy of Transurethral Resection of the Prostate Combined with Oral Anticholinergics or Botulinum Toxin – A Injection to Treat Benign Prostatic Hyperplasia with Overactive Bladder: A Case–Control Study

Figures & data

Table 1 Baseline and Demographic Characteristics

Variables	TURP+Solifenacin N=18		TURP+Dysport N=21		P
Age, year	68.50±6.51		71.71±7.47		0.164
Prostate Volume, mL	53.03±11.23		57.10±03.07		0.231
Qmax	11.01±2.05		11.07±1.12		0.218
BCI*	164±17.01		161±16.06		0.103
OAB type	III: 14	IV:4	III:17	IV:4	0.558
PVR	86.6±23.31		87.02±19.07		0.127
IPSS	24.5±6.75		24.86±5.16		0.853
Urgency	4.22±0.64		4.24±0.70		0.942
Frequency	4.08±0.31		4.03±0.55		0.921
Nocturia	4.17±0.08		4.11±0.10		0.948
QoL	4±1		4±1		0.901

Note: *Bladder contractility index.

Table 2 Changes in Storage Symptoms at Months 6 and 9 in the Case Arm and Comparison with Baseline

Variables	TURP+Dysport N=21			P
	Baseline	6 Months	9 Months	6 Months	9 Months
PVR	87.02±19.07	33.41±13.28	42.07±18.02	0.000	0.000
IPSS	24.86±5.16	5.1±2.07	8.2±1.19	0.000	0.000
Urgency	4.24±0.70	1.67±1.27	2±1.86	0.000	0.001
Frequency	4.03±0.55	2.01±0.06	2.15±1.13	0.000	0.000
Nocturia	4.11±0.10	2.00±0.86	2.93±0.43	0.000	0.01
Incontinence	15	3	4	0.000	0.000
QoL	4±1	2±0.07	2±1.07	0.000	0.001

Table 3 Changes in Storage Symptoms at Months 6 and 9 in the Control Arm and Comparison with Baseline

Variables	TURP+Solifenacin N=18			P
	Baseline	6 Months	9 Months	6 Months	9 Months
PVR	86.6±23.31	41.07±18.09	66.26±10.22	0.000	0.001
IPSS	24.5±6.75	7±3.23	11±1.02	0.000	0.003
Urgency	4.22±0.64	3.78±1.39	4.64±1.91	0.02	0.3
Frequency	4.08±0.31	2.51±1.22	2.91±1.09	0.001	0.01
Nocturia	4.17±0.08	2.76±1.09	2.9±2.36	0.001	0.01
Incontinence	17	9	12	0.000	0.008
QoL	4±1	2±0.3	3±1.04	0.002	0.01

Table 4 Changes in the Storage Symptoms at Months 6 and 9 in Case and Control Groups

Variables	TURP+Solifenacin N=18		TURP+Dysport N=21		P
	6 Months	9 Months	6 Months	9 Months	6 Months	9 Months
PVR	41.07±18.09	66.26±10.22	33.41±13.28	42.07±18.02	0.01	0.005
IPSS	7±3.23	11±1.02	5.1±2.07	8.2±1.19	0.033	0.01
Urgency	3.78±1.39	4.64±1.91	1.67±1.27	2±1.86	0.000	0.001
Frequency	2.51±1.22	2.91±1.09	2.01±0.06	2.15±1.13	0.05	0.01
Nocturia	2.76±1.09	2.9±2.36	2.00±0.86	2.93±0.43	0.01	0.33
Incontinence	9	12	3	4	0.003	0.000
QoL	2±0.3	3±1.04	2±0.07	2±1.07	0.4	0.06