Overexpression of Adiponectin Receptors in Opium Users with and without Cancer

Figures & data

Table 1 Demographic Characteristics of Opium Users (Case) and Non-Opium Users (Controls)

Variables	Cases (N=100)	Controls (N=100)	P-value
Gender			0.264
Male	77	69
Female	23	31
Age (year)	52.6 ± 9.7	50.2 ± 10.1	0.088
BMI (kg/m2)	22.4 ± 3.2	23.2 ± 2.8	0.061
Marital status (N)			0.369
Married	63	70
Single or divorced	29	25
Widow	8	5
Alcohol consumption (N)			0.151
Never use	53	64
Seldom use	47	36
Smoking (N)	33	22	0.112
Diabetes (N)	13	15	0.838
History of stroke (N)	5	2	0.444
Endocrine diseases (N)	9	6	0.593

Table 2 Demographic Characteristics of Opium Users Diagnosed with Cancer and Cancer-Free Opium Users

Variables	Opium Users with Cancer (N=8)	Cancer-Free Opium Users (N=92)	P-value
Gender			0.995
Male	6	71
Female	2	21
Age (year)	50.6 ± 8.7	51.3 ± 9.2	0.836
BMI (kg/m2)	21.4 ± 2.2	22.5 ± 2.4	0.214
Marital status (N)			0.142
Married	5	58
Single or divorced	2	27
Widow	1	7
Alcohol consumption (N)			0.991
Never use	4	49
Seldom use	4	43
Smoking (N)	7	26	0.779
Diabetes (N)	4	9	0.902
History of stroke (N)	2	3	0.785
Endocrine diseases (N)	3	6	0.780

Table 3 Expression of AdipoR1 and AdipoR2 in Opium Users (Case) and Non-Opium Users (Controls)

	Case N=100	Controls N=100	P-value
	Mean ± SD	Mean ± SD
AdipoR1	76.76 ± 15.30	22.10 ± 2.01	P<0.0001
AdipoR2	78.74 ± 16.25	25.50 ± 2.38	P<0.0001

Table 4 Expression of AdipoR1 and AdipoR2 in Opium Users Diagnosed with Cancer and Cancer-Free Opium Users Not Developing Malignancies

	Opium Users Diagnosed with Cancer	Cancer-Free Opium Users	P-value
	Mean ± SD	Mean ± SD
AdipoR1	97.1 ± 2.2	75.5 ± 14.7	P=0.0001
AdipoR2	95.1 ± 3.8	77.2 ± 16.1	P=0.0001