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REVIEW

Flavonoids and Gastric Cancer Therapy: From Signaling Pathway to Therapeutic Significance

, , , , , , , & show all
Pages 3233-3253 | Received 01 Mar 2024, Accepted 01 Jul 2024, Published online: 24 Jul 2024

Figures & data

Figure 1 The potential role of flavonoids for GC therapy. Flavonoids exert a regulatory role in modulating various phenotypes of GC, encompassing tumor growth, proliferation, invasion, metastasis, angiogenesis, and cell death. Created by Biorender.com.

Figure 1 The potential role of flavonoids for GC therapy. Flavonoids exert a regulatory role in modulating various phenotypes of GC, encompassing tumor growth, proliferation, invasion, metastasis, angiogenesis, and cell death. Created by Biorender.com.

Figure 2 Chemical structures of representative flavonoids that prevent GC by modulating tumor growth, proliferation, invasion, metastasis, and angiogenesis. Created by Biorender.com.

Figure 2 Chemical structures of representative flavonoids that prevent GC by modulating tumor growth, proliferation, invasion, metastasis, and angiogenesis. Created by Biorender.com.

Figure 3 Chemical structures of representative flavonoids that prevent GC by modulating cell death. Created by Biorender.com.

Figure 3 Chemical structures of representative flavonoids that prevent GC by modulating cell death. Created by Biorender.com.

Table 1 Profiles of Flavonoids Inhibiting GC

Figure 4 Mechanisms of flavonoids suppressing GC by inhibiting tumor growth and proliferation, invasive migration, and angiogenesis. Created by Biorender.com.

Figure 4 Mechanisms of flavonoids suppressing GC by inhibiting tumor growth and proliferation, invasive migration, and angiogenesis. Created by Biorender.com.

Figure 5 Mechanisms of flavonoids suppressing GC by inducing cell death inducing apoptosis, autophagy, ferroptosis, and pyroptosis. Created by Biorender.com.

Figure 5 Mechanisms of flavonoids suppressing GC by inducing cell death inducing apoptosis, autophagy, ferroptosis, and pyroptosis. Created by Biorender.com.

Table 2 Profiles of Flavonoids Combined Other Drugs Inhibiting GC