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Drug Design, Development and Therapy Volume 8, 2014 - Issue
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Original Research

A preliminary study of painless and effective transdermal botulinum toxin A delivery by jet nebulization for treatment of primary hyperhidrosis

Tommaso Iannitti1 School of Biomedical Sciences, University of Leeds, Leeds, UK;2 Poliambulatorio del Secondo Parere, Modena, ItalyCorrespondence[email protected]
,
Beniamino Palmieri3 Department of Surgery and Surgical Specialties, University of Modena and Reggio Emilia Medical School, Surgical Clinic, Modena, Italy
,
Anna Aspiro3 Department of Surgery and Surgical Specialties, University of Modena and Reggio Emilia Medical School, Surgical Clinic, Modena, Italy
&
Alessandro Di Cerbo2 Poliambulatorio del Secondo Parere, Modena, Italy;3 Department of Surgery and Surgical Specialties, University of Modena and Reggio Emilia Medical School, Surgical Clinic, Modena, Italy
Pages 931-935 | Published online: 14 Jul 2014

Figures & data

Figure 1 Treatment of primary palmar (A), axillary (B), and plantar (C) hyperhidrosis with lidocaine and botulinum toxin A delivered by JetPeel™-3.

Note: JetPeel™-3 is manufactured by TavTech Ltd., Yehud, Israel.
Figure 1 Treatment of primary palmar (A), axillary (B), and plantar (C) hyperhidrosis with lidocaine and botulinum toxin A delivered by JetPeel™-3.

Figure 2 (A) Delivery of lidocaine and BTX-A by JetPeel™-3 results in lower procedure-related pain versus delivery of lidocaine by JetPeel™-3 followed by BTX-A injections; (B) delivery of lidocaine and BTX-A by JetPeel™-3 decreases sweating at 3-month follow-up versus lidocaine delivered by JetPeel™-3 followed by multiple BTX-A injections; (C) patients are more satisfied with the protocol based on delivery of lidocaine and BTX-A by JetPeel™-3, if compared with the procedure based on delivery of lidocaine by JetPeel™-3 followed by BTX-A injections.

Notes: Data are presented as the means ± standard error of the mean. ***P<0.001. JetPeel™-3 is manufactured by TavTech Ltd., Yehud, Israel.
Abbreviation: VAS, visual analog scale.
Figure 2 (A) Delivery of lidocaine and BTX-A by JetPeel™-3 results in lower procedure-related pain versus delivery of lidocaine by JetPeel™-3 followed by BTX-A injections; (B) delivery of lidocaine and BTX-A by JetPeel™-3 decreases sweating at 3-month follow-up versus lidocaine delivered by JetPeel™-3 followed by multiple BTX-A injections; (C) patients are more satisfied with the protocol based on delivery of lidocaine and BTX-A by JetPeel™-3, if compared with the procedure based on delivery of lidocaine by JetPeel™-3 followed by BTX-A injections.

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